Results 91 to 100 of about 678,195 (314)
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Eine Informationsbasis für zeitoptimiertes Incident Management
, 2003 Ziel des Incident Managements ist die schnellstmögliche Wiederherstellung des regelmäßigen Betriebs eines Services nach Eintritt eines Vorfalls. Eine bewusst oder unbewusst produzierte Falschmeldung über einen sicherheitskritischen Vorfall kann jedoch zu
Scholz, Peter, Mörl, Ramon
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Inflammatory markers and incident frailty in men and women:the English Longitudinal Study of Ageing [PDF]
, 2013 Cross-sectional studies show that higher blood concentrations of inflammatory markers tend to be more common in frail older people, but longitudinal evidence that these inflammatory markers are risk factors for frailty is sparse and inconsistent.
Gale, Catharine R +8 more
core +1 more source
Pan Am flight 103 investigation and lessons learned
Aviation, 2009 On 21 December 1988, one of the most tragic incidents in the history of civil aviation took place. But the lessons of that tragic day and the impact of “Pan Am 103” or “Lockerbie” remain valuable and deserve attention. Santrauka 1988 m. gruodžio 21
Sergey Ushynskyi
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Prevalence and incidence [PDF]
BMJ, 2010 A randomised controlled trial investigated whether screening and treating women for chlamydial infection reduced the subsequent occurrence of pelvic inflammatory disease.1 Between 2004 and 2006, vaginal swabs were provided by 2529 sexually active female students. The samples were randomly allocated to immediate testing (screening group), or storage and
openaire +2 more sources
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source
EIRS: Ewaso Incident Reporting System
, 2004 Ewaso Incident Reporting System: reports on human-elephant interaction in ...
Olwero, Nasser, Georgiadis, Nicholas
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