Results 91 to 100 of about 2,213,662 (293)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Interference of surface plasmon polaritions controlled by the phase of incident light

, 2008
Interference patterns of surface plasmon polaritons(SPPs) are observed in the extraordinary optical transmission through subwavelength holes in optically thick metal plate. It is found that the phase of incident light can be transferred to SPPs.
Bouhelier A., Guang-Can Guo, Guo-Ping Guo, Pei Zhang, Xi-Feng Ren, Yun-Feng Huang, Zhi-Wei Wang   +6 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Correction to: Morbidity and mortality outcomes of COVID-19 patients with and without hypertension in Lagos, Nigeria: a retrospective cohort study

Global Health Research and Policy, 2021
Akin Abayomi, Akin Osibogun, Oluchi Kanma-Okafor, Jide Idris, Abimbola Bowale, Ololade Wright, Bisola Adebayo, Mobolanle Balogun, Segun Ogboye, Remi Adeseun, Ismael Abdus-Salam, Bamidele Mutiu, Babatunde Saka, Dayo Lajide, Sam Yenyi, Rotimi Agbolagorite, Oluwatosin Onasanya, Eniola Erinosho, Joshua Obasanya, Olu Adejumo, Sunday Adesola, Yewande Oshodi, Iorhen E. Akase, Shina Ogunbiyi, Adenike Omosun, Femi Erinoso, Hussein Abdur-Razzaq, Nike Osa, Kingsley Akinroye   +28 more
doaj   +1 more source

DNA Methylation Algorithms of Aging and Incident Cardiovascular Disease: A Prospective Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background While DNA methylation (DNAm)‐based algorithms of aging show promise for predicting age‐related diseases, their comparative utility for incident cardiovascular disease (CVD) remains underexplored.
Xian Cui, Chunbei Yi, Hui Zhang, Yaqian Xu, Chongyu Ding, Zhaojun Wang, Shiqun Sun, Xiangwei Li   +7 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Continuity of Operations in Newborn Screening: Lessons Learned from Three Incidents

International Journal of Neonatal Screening
Three incidents that impacted two US newborn screening (NBS) programs highlight the importance of contingency planning for the continuity of operations (COOP).
M. Christine Dorley, Elizabeth Bair, Patricia Ryland, Amanda D. Ingram, Emily Reeves, Kara J. Levinson, Ona O. Adair, Jenny F. Meredith, Susanne Crowe   +8 more
doaj   +1 more source

Stimulated Emission from a single excited atom in a waveguide

, 2012
We study stimulated emission from an excited two-level atom coupled to a waveguide containing an incident single-photon pulse. We show that the strong photon correlation, as induced by the atom, plays a very important role in stimulated emission ...
A. Einstein, A. E. Siegman, B. E. A. Saleh, Eden Rephaeli, Shanhui Fan   +4 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Teaching ultrasonics using spreadsheets [PDF]

, 2012
Whenever an ultrasonic wave encounters a boundary between two media it is partially reflected and refracted, as any acoustic wave would be. Unlike light, the wave also undergoes mode conversion so that in the general case a single incident wave could ...
Picton, Philip
core