Results 51 to 60 of about 452,695 (313)

Use of Closed-Incision Negative-Pressure Therapy in Aesthetic Surgery

open access: yes, 2019
Recently published studies have demonstrated clinical effectiveness of closed-incision negative-pressure therapy (ciNPT) in many fields of surgery including vascular, cardiac, colorectal, orthopedic, and reconstructive surgery.
Virginia Lobach   +5 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Wound Dehiscence and Iris Prolapse Through Side-Port Incision 5 Years After Phacoemulsification Surgery: Case Repor [PDF]

open access: yes, 2013
A 65-year-old man was referred to our institution for the evaluation of redness in the right eye. The patient sustained a blunt trauma 10 days previously and had a history of bilateral uncomplicated phacoemulsification performed 5 years earlier.
Osman Melih Ceylan   +2 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

La morphologie karstique dans le canyon de la Cèze et sur le plateau de Méjannes-le-Clap (Garrigues nord, Gard, France) – Rapports avec l'évolution paléogéographique mio-pliocène

open access: yesPhysio-Géo, 2008
The limestone Méjannes-le-Clap plateau is incised by the Cèze canyon. A study of the plateau has shed new light on the paleogeographic evolution of the south-western edge of the French Massif Central between the development of the Miocenian erosion ...
Joël Jolivet, Claude Martin
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

A Collaborative Quality Improvement Project to Reduce Surgical Site Infection in Cesarean Delivery

open access: yesWomen's Health Reports
Introduction: Cesarean delivery (CD) facilitates delivery of the baby through an incision and is performed in situations where vaginal delivery poses risks to the mother, baby, or both.
Jeanette Harris, Mandy Spitzer
doaj   +1 more source

Precipitant-Free Crystallization of Protein Molecules Induced by Incision on Substrate

open access: yesCrystals, 2017
Nucleation of protein crystals has been shown to be facilitated by substrates decorated with both nano- to micro-scale hierarchical undulations and spatially varying surface potential. In fact, on such surfaces, several proteins were found to crystallize
Anindita Sengupta Ghatak   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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