Results 211 to 220 of about 27,787 (266)

The ultrarapid delayed rectifier potassium current has important functional role in the repolarization reserve of canine and human ventricular muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular ...
Alaa Amin E. Abdelmagid   +17 more
wiley   +1 more source

Synchrony within Aβ mechanoreceptor subtypes governs signal propagation to primary somatosensory cortex

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We used an optogenetic gain‐of‐function manipulation to investigate how sensory signals from two subtypes of Aβ low threshold mechanoreceptors (LTMRs) contribute to the cortical representation of touch. CatCh, a sensitive and fast channelrhodopsin variant, enables pulsed‐light generation of high‐frequency action potential trains ...
Wanyi Liu   +2 more
wiley   +1 more source

Myocardial stretch‐induced ROS production is enhanced prior to the development of heart failure under TAC‐induced pressure overload

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend To elucidate the relationship between oxidative stress in heart failure induced by chronic mechanical overload and physiological NOX2‐derived stretch‐induced reactive oxygen species (ROS) that support myocardial contractility during acute stretch, we investigated the changes in stretch‐induced ROS following transverse aortic ...
Yumiko Chiba   +4 more
wiley   +1 more source

Bethesda Endoscopic Retrograde Cholangiopancreatography Skill Assessment Tool (BESAT)‐Based Simulator Training Using a Novel Dry Endoscopic Retrograde Cholangiopancreatography Model Improves Technical Proficiency and Self‐Efficacy: A Prospective Study

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Endoscopic sphincterotomy (EST) is a high‐risk procedure with a steep learning curve. We previously developed a novel dry simulator capable of reproducing bleeding after an inappropriate incision. This study aimed to evaluate the effectiveness of a structured educational program using the simulator within the Bethesda Endoscopic ...
Yutaka Hatayama   +9 more
wiley   +1 more source

Mountains of diversity: a systematic revision of the Andean rodent genus <i>Oreoryzomys</i> (Cricetidae: Sigmodontinae). [PDF]

open access: yesPeerJ
Brito J   +8 more
europepmc   +1 more source

Post‐Endoscopic Retrograde Cholangiopancreatography Bleeding After Endoscopic Stone Removal in Dialysis Patients: A Multicenter Retrospective Study

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Post‐endoscopic retrograde cholangiopancreatography (post‐ERCP) bleeding occurs more frequently in dialysis patients than in non‐dialysis patients. This study aimed to identify risk factors for post‐ERCP bleeding following stone removal in patients undergoing dialysis.
Masaki Nishimura   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy