Results 141 to 150 of about 237,975 (302)

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Transforming Grain‐Boundary Brittle Precipitates to Ductility Pathways in Complex Concentrated Alloy

Advanced Science, EarlyView.
By engineering graded BCC/L12 interfaces, brittle precipitates in a complex concentrated alloy enable sequential deformation, realizing gigapascal strength with >20% elongation to solve the strength‐ductility trade‐off. ABSTRACT Conventional wisdom holds that hard grain‐boundary (GB) precipitates embrittle structural alloys by acting as crack ...
Zhixin Li, Xiao‐Tong Li, Zhaoqi Chen, Yushan Geng, Hao Gong, Sijia Hu, Wenli Song, Wanshun Xia, Chuanzheng Li, Linfa Peng, Yue Fan, Pengfei Guan, Bo Zhang, Weihua Wang, Yong Yang   +14 more
wiley   +1 more source

Applications of FEM and BEM in two-dimensional fracture mechanics problems [PDF]

A comparison of the finite element method (FEM) and boundary element method (BEM) for the solution of two-dimensional plane strain problems in fracture mechanics is presented in this paper.
Min, J. B., Steeve, B. E., Swanson, G. R.   +2 more
core   +1 more source

Programmable Multifunctional Bistable Structures for Energy Transfer and Dissipation

Advanced Science, EarlyView.
Utilizing the energy conversion characteristics of asymmetric bistable beams, this study develops a programmable multifunctional system composed of multiple bistable beams for energy transfer and dissipation. The high energy density enables the system to demonstrate potential in transient scenarios such as target delivery and shock absorption ...
Xin Na, Jincong Zhang, Zhicheng Chen, Venkatarao Selamneni, Haotian Chen, Hadi Heidari, Morteza Amjadi   +6 more
wiley   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

In vitro comparative study on the friction of stainless steel wires with and without Orthospeed® (JAL 90458) on an inclined plane. [PDF]

J Clin Exp Dent, 2016
Alió-Sanz JJ, Claros-Stucchi M, Albaladejo A, Iglesias-Conde C, Alvarado-Lorenzo A.   +4 more
europepmc   +1 more source

Natural Variations of ZmRLR1 Mediate the Root Lodging Resistance of Maize by Regulating Root Ascorbate and Auxin Homeostasis

Advanced Science, EarlyView.
Root lodging severely limits crop yield and quality. We reveal that ZmRLR1, a plasma membrane b‐type cytochrome, regulates lodging resistance in maize through dual roles: modulating intracellular redox balance and functioning as a novel component of clathrin‐mediated endocytosis to influence auxin homeostasis. Moreover, natural variations in the ZmRLR1
Wenshuai Lv, Pengshuai Yan, Huan Chen, Guangxian Li, Yiyue Zhao, Yanhui Chen, Wen‐Xue Li, Qingguo Du   +7 more
wiley   +1 more source

Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis

Advanced Science, EarlyView.
β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen, Haidong Yu, Dongjiang Lin, Guojun Yang, Yuchen Xie, Yang Zhang, Jifeng Yuan   +6 more
wiley   +1 more source

Feline‐Inspired Robot Enabled by Combustion‐Driven Actuators for Agile Motion and High‐Payload Obstacle Traversal

Advanced Science, EarlyView.
Inspired by nature's competitive maneuvers, this study introduces a combustion‐driven soft actuator that powers a multi‐modal “Jump‐and‐Fly Catbot” (JFC). With millisecond response, high‐force output (over 70 times its weight) and precise control (error within 5%), the robot can jump, fly, hover, and escape from challenging environments, achieving ...
Hongkuan Ma, Yang Yang, Zhiguo He, Hongliang Ren, Pengcheng Jiao   +4 more
wiley   +1 more source