Results 111 to 120 of about 260,941 (267)

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

Clinical Anatomy, EarlyView.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis

Clinical Pharmacology &Therapeutics, EarlyView.
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic, Deanne Nixie R. Miao, Britt I. Drögemöller, Alain Dabdoub, Julia M. Abitbol   +4 more
wiley   +1 more source

Advances in epidemiology and population-based prevention and control of cancers caused by asbestos exposure

生物医学转化
Asbestos is a collective term for six natural mineral fibers that have been widely used commercially. These fibers are classified into two main groups: amphibole asbestos (including crocidolite, tremolite, actinolite, anthophyllite, and amosite) and ...
Huang Qiulin, Lian Fuzhi, Chen Tianhui
doaj   +1 more source

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou, Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Mariam R. Habil, Giannoulis Fakis, Rodney F. Minchin, David W. Hein, Sotiria Boukouvala, Andrea Gaedigk   +14 more
wiley   +1 more source

Gene-environment interactions and colorectal cancer risk: A case-control study on xenobiotic metabolizing enzyme polymorphisms in the Jammu& Kashmir, India population

Advances in Biomarker Sciences and Technology
Background: Cancer remains a significant global health concern, with colorectal cancer (CRC) showing a rising incidence, particularly among younger populations. Most CRC cases are linked to a complex interplay of genetic and environmental factors.
Gowhar Rashid, Gulzar A. Bhat, Tahseen Bilal Rather, Kulsum Akhter, Ishrat Parveiz, Irfan Maqbool, Syed Nisar Ahmad, Malik Tariq Rasool, Farooq Ahmad Jan, Syed Mudassar   +9 more
doaj   +1 more source

Do Firms Hoard Cash Under Environmental Pressure? Insights From GHG Emissions and Greenwashing Activities

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Environmental accountability has become a global priority, with governments implementing policies like the Kyoto Protocol and the Paris Agreement. However, many firms continue to operate outside environmentally ethical standards, facing potential regulatory, financial, and reputational risks.
Ones Amri, Davide Calandra, Paolo Biancone, Hasna Chaibi   +3 more
wiley   +1 more source

Towards health impact assessment of drinking-water privatization: the example of waterborne carcinogens in North Rhine-Westphalia (Germany)

Bulletin of the World Health Organization, 2003
Worldwide there is a tendency towards deregulation in many policy sectors - this, for example, includes liberalization and privatization of drinking-water management.
Fehr Rainer, Mekel Odile, Lacombe Martin, Wolf Ulrike   +3 more
doaj  

Pesticide Contamination in the Hair of Children From Colonia San Juan, a Rural Community in Paraguay

Drug Testing and Analysis, EarlyView.
Hair analysis in children from a rural community in Paraguay reveals exposure to organophosphates, pyrethroids, neonicotinoids, fungicides, herbicides, and endocrine disruptors, highlighting the urgent need for stricter environmental protections and preventive health measures. ABSTRACT Chronic exposure to pesticides can cause carcinogenic, reproductive,
Stela Benitez Leite, Alba Iglesias‐Gonzalez, Mirta Noemí Mesquita, María Luisa Macchi, Robin Mesnage, Brice M. R. Appenzeller   +5 more
wiley   +1 more source

Relationship of smokeless tobacco uses in the perspective of oral cancer: A global burden

Oral Oncology Reports
Smokeless tobacco (SLT) use represents a significant and often overlooked public health concern, particularly in regions where cultural practices and societal norms endorse its consumption.
Ashek Elahi Noor, Boyapati Ramanarayana
doaj   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source