Results 201 to 210 of about 277,495 (246)

KAT2A Promotes the Progression of Renal Cell Carcinoma by Regulating the Succinylation of SERPINE2

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Epithelial‐mesenchymal transition (EMT) and angiogenesis are critical drivers of renal cell carcinoma (RCC) progression, yet their upstream regulatory mechanisms remain incompletely understood. This study aimed to investigate the role of KAT2A in RCC and elucidate the underlying molecular mechanism by which it promotes tumor progression.
Chang‐Cheng Liu, Xue‐Dong Li
wiley   +1 more source

Complete Response to Intravesical BCG for High-Risk pT1 Bladder Cancer With Lymphovascular Invasion: A Case Report. [PDF]

Case Rep Oncol Med
Saad A, Daraan FM, Barghouth I, Sleiay M.   +3 more
europepmc   +1 more source

Chemical Ionization Mass Spectrometry: Fundamental Principles, Diverse Applications, and the Latest Technological Frontiers

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt, Adriana Arigò, Giorgio Famiglini, Pierangela Palma, Achille Cappiello   +4 more
wiley   +1 more source

Comparative Carcinogenic Risk Assessment of Polycyclic Aromatic Hydrocarbons Accumulation in Normal and Cancerous Lung Tissues of Patients from Northern Thailand. [PDF]

Toxics
Yabueng N, Samakarn Y, Pairojtanachai K, Kraisitnitikul P, Kabao J, Tajarernmuang P, Supphapipat A, Siwachat S, Saeteng S, Chantara S, Tantraworasin A.   +10 more
europepmc   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Rethinking the microenvironment's role in chemical-induced malignancy. [PDF]

Toxicol Sci
Bisson WH, Currie RA, Lim EL, Mlynarczyk C, Tokar EJ, Colacci A, Colacino JA.   +6 more
europepmc   +1 more source

Characteristics, properties and limitations of per‐ or polyfluoroalkyl substances (PFASs) and fluoropolymers

Polymer International, EarlyView.
An overview and categorization of man‐made per‐ or polyfluoroalkyl substances (PFASs) including low‐molar‐mass and high‐molar‐mass fluorochemicals, and their international regulations is presented. Though certain PFASs are toxic, bioaccumulative and cross the human cellular membranes, others, such as fluoropolymers, are safe, reliable and involved in ...
Bruno Améduri
wiley   +1 more source

Genetic Polymorphisms and Antioxidant Reactions in Prostate Cancer. [PDF]

Int J Mol Sci
Kamiński P, Dróżdż-Afelt J, Gorzelańczyk EJ, Baszyński J, Tkaczenko H, Hromada M, Nuszkiewicz J, Woźniak A, Kurhaluk N.   +8 more
europepmc   +1 more source

Expert consensus on clinical trial design guidelines for FLASH radiotherapy

Precision Radiation Oncology, EarlyView.
• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Hui Luo, Chen Cheng, Chengliang Yang, Bing Li, Jiandong Zhang, Jinbo Yue, Zhaoyang Lou, Hui Liu, Jing Cai, Hong Ge   +9 more
wiley   +1 more source

Occupational exposure to chlorinated solvents and lung cancer: results of the SYNERGY case-control study. [PDF]

Occup Environ Med
Wan W, Vermeulen R, Portengen L, Olsson A, Schüz J, Bijoux W, Ahrens W, Barul C, Behrens T, Brüning T, Caporaso NE, Consonni D, Demers PA, Fabianova E, Fernández-Tardón G, Field J, Forastiere F, Foretova L, Ge CB, Gustavsson P, Janout V, Jöckel KH, Karrasch S, Kendzia B, Landi MT, Lissowska J, Mates D, McLaughlin J, Merletti F, Migliore E, Pándics T, Pohlabeln H, Radoï L, Richiardi L, Schejbalova M, Siemiatycki J, Świątkowska B, Wichmann HE, Zaridze D, Straif K, Kromhout H, Peters S.   +41 more
europepmc   +1 more source