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Pancreatology, 2008 Pancreatic cancer is an almost universally lethal disease. Research over the last two decades has shown that pancreatic cancer is fundamentally a genetic disease, caused by inherited germline and acquired somatic mutations in cancer-associated genes. Multiple alterations in genes that are important in pancreatic cancer progression have been identified,
Jan-Bart M, Koorstra +3 more
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Long noncoding RNAs involvement in Epstein-Barr virus infection and tumorigenesis
Virology Journal, 2020 The Epstein-Barr virus (EBV) is a ubiquitous γ-herpesvirus related to various types of cancers, including epithelial nasopharyngeal carcinoma, gastric carcinoma, and lymphoma. Long noncoding RNAs (lncRNAs) are expressed extensively in mammalian cells and
Jing Zhang +7 more
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Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2003 Cadmium is a heavy metal of considerable environmental and occupational concern. Cadmium compounds are classified as human carcinogens by several regulatory agencies. The most convincing data that cadmium is carcinogenic in humans comes from studies indicating occupational cadmium exposure is associated with lung cancer.
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Cell & Bioscience, 2019 Mitochondria are energy factories of cells and are important pivots for intracellular interactions with other organelles. They interact with the endoplasmic reticulum, peroxisomes, and nucleus through signal transduction, vesicle transport, and membrane ...
MengFang Xia +5 more
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Environment InternationalCarbon black nanoparticles (CBNPs) have been demonstrated to induce DNA damage in epithelial cells. However, the potential of the damage to initiate carcinogenesis and the underlying mechanism remain poorly understood.
Han Zhang +12 more
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Вопросы вирусологии, 2020 Introduction. Molecular studies have shown that viruses appeared in the early stages of the evolution of life. For millions of years, viruses have evolved by changing old and acquiring new sequences in their RNA or DNA.
Kseniya V. Smirnova +4 more
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Circulating trans fatty acids are associated with prostate cancer in Ghanaian and American men
Nature Communications, 2023 The association between fatty acids and prostate cancer remains poorly explored in African-descent populations. Here, we analyze 24 circulating fatty acids in 2934 men, including 1431 prostate cancer cases and 1503 population controls from Ghana and the ...
Tsion Zewdu Minas +22 more
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Discover OncologyHepatocellular carcinoma (HCC) remains a global health challenge owing to its widespread incidence and high mortality. HCC has a specific immune tolerance function because of its unique physiological structure, which limits the efficacy of chemotherapy ...
Minni Zhang +5 more
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Tumor Associated Macrophages in Kidney Cancer
Analytical Cellular Pathology, 2016 Tumor associated macrophages (TAMs) are an important element of tumor stroma. They originate from blood monocytes attracted by chemokines and cytokines produced by tumor cells and, being instructed by tumor microenvironment, develop into potent tumor ...
Olga V. Kovaleva +3 more
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Systematic evaluation of RNA-Seq preparation protocol performance
BMC Genomics, 2019 Background RNA-Seq is currently the most widely used tool to analyze whole-transcriptome profiles. There are numerous commercial kits available to facilitate preparing RNA-Seq libraries; however, it is still not clear how some of these kits perform in ...
Hsueh-Ping Chao +13 more
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