Results 21 to 30 of about 542,674 (361)

Circular RNA 406961 interacts with ILF2 to regulate PM2.5-induced inflammatory responses in human bronchial epithelial cells via activation of STAT3/JNK pathways

Environment International, 2020
Fine particulate matter (PM2.5) has been verified to augmented the incidence of pneumonia, asthma, pulmonary fibrosis, and other pulmonary diseases. Airway inflammation is the pathological basis of the respiratory system, and understanding the molecular ...
Yangyang Jia, Xin Li, Aruo Nan, Nan Zhang, Lijian Chen, Hanyu Zhou, Han Zhang, Miaoyun Qiu, Jialu Zhu, Yihui Ling, Yiguo Jiang   +10 more
doaj   +1 more source

Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved [PDF]

, 2011
Red meat and processed meat intake is associated with a risk of colorectal cancer, a major cause of death in affluent countries. Epidemiological and experimental evidence supports the hypothesis that heme iron present in meat promotes colorectal cancer ...
Bingham, Chen, Clinton, Cross, Cummings, de Vogel, Denis E. Corpet, Douglass, Fabrice H.F. Pierre, Grant, Leuratti, Marnett, Mirvish, Nadia M. Bastide, Nauss, Nutter, Parnaud, Pierre, Pierre, Sandhu, Sawa, Schwartz, Sesink, Shuker, Sinha   +24 more
core   +4 more sources

Ropivacaine promotes apoptosis of hepatocellular carcinoma cells through damaging mitochondria and activating caspase-3 activity

Biological Research, 2019
Background Recent evidences indicated that some local anaesthetic agents played a role in inhibiting the proliferation of cancer cells; Whether ropivacaine is able to promote apoptosis of hepatocellular carcinoma (HCC) cells is still unclear.
Wenting Wang, Mingyue Zhu, Zhixin Xu, Wei Li, Xu Dong, Yi Chen, Bo Lin, Mengsen Li   +7 more
doaj   +1 more source

X or Y Cancer: An Extensive Analysis of Sex Differences in Lung Adenocarcinoma

Current Oncology, 2023
Background: Cellular metabolism is a tightly controlled process during which cell growth and survival are maintained. Lung cancer is a disease with clear sex differences, where female patients have better survival rates than males.
Raneem Yaseen Hammouz, Magdalena Orzechowska, Dorota Anusewicz, Andrzej K. Bednarek   +3 more
doaj   +1 more source

Optimization Aspects of Carcinogenesis

, 2009
Any process in which competing solutions replicate with errors and numbers of their copies depend on their respective fitnesses is the evolutionary optimization process.
Brutovsky, B., Horvath, D.
core   +3 more sources

Nickel carcinogenesis [PDF]

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2003
Human exposure to highly nickel-polluted environments, such as those associated with nickel refining, electroplating, and welding, has the potential to produce a variety of pathologic effects. Among them are skin allergies, lung fibrosis, and cancer of the respiratory tract.
Kazimierz S, Kasprzak, F William, Sunderman, Konstantin, Salnikow   +2 more
openaire   +2 more sources

Non melanoma skin cancer pathogenesis overview [PDF]

, 2018
(1)Background: Non-melanoma skin cancer is the most frequently diagnosed cancer in humans. The process of skin carcinogenesis is still not fully understood.
Bottoni Ugo, Cantisani Carmen, Didona Dario, Paolino Giovanni   +3 more
core   +1 more source

Author Correction: De novo identification of essential protein domains from CRISPR-Cas9 tiling-sgRNA knockout screens

Nature Communications, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Wei He, Liang Zhang, Oscar D. Villarreal, Rongjie Fu, Ella Bedford, Jingzhuang Dou, Anish Y. Patel, Mark T. Bedford, Xiaobing Shi, Taiping Chen, Blaine Bartholomew, Han Xu   +11 more
doaj   +1 more source

A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer

Scientific Reports, 2021
Resistance to drugs targeting the androgen receptor (AR) signaling axis remains an important challenge in the treatment of prostate cancer patients. Activation of alternative growth pathways is one mechanism used by cancer cells to proliferate despite ...
Sander A. L. Palit, Jeroen van Dorp, Daniel Vis, Cor Lieftink, Simon Linder, Roderick Beijersbergen, Andries M. Bergman, Wilbert Zwart, Michiel S. van der Heijden   +8 more
doaj   +1 more source

Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b) [PDF]

, 2009
Cyclin D1b is an alternative transcript of the cyclin D1 gene (CCND1) expressed in human tumors. Its abundance is regulated by a single base pair polymorphism at the exon 4/intron 4 boundary (nucleotide 870).
Benavides, Fernando, Blando, Jorge, Cardenas, Kim, Conti, Claudio, Johnson, David G., Knudsen, Erik S., Pérez, Carlos, Richie, Ellen, Rodriguez Puebla, Marcelo L., Rojas, Paola Andrea, Senderowicz, Adrian M.   +10 more
core   +1 more source