Results 21 to 30 of about 327,951 (318)
Concentration and isolation of DNA from biological fluids by agarose gel isotachophoresis
BioTechniques, 2005 Isotachophoresis is an electrophoretic method of separation of charged substances. The method is characterized by a discontinuous buffer system, constant velocity of separated molecules, and the distribution of separated components in the form of narrow ...
Valentina N. Kondratova +3 more
doaj +1 more source
Nature Communications, 2023 The SWI/SNF ATP-dependent chromatin remodeler is a master regulator of the epigenome, controlling pluripotency and differentiation. Towards the C-terminus of the catalytic subunit of SWI/SNF is a motif called the AT-hook that is evolutionary conserved ...
Dhurjhoti Saha +13 more
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How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men [PDF]
, 2005 Tumours in rodent and human colon share many histological and genetic features. To know if rodent models of colon carcinogenesis are good predictors of chemopreventive efficacy in humans, we made a meta-analysis of aspirin, beta-carotene, calcium, and ...
Denis E. Corpet +4 more
core +1 more source
Mathematical methods and models for radiation carcinogenesis studies [PDF]
, 1986 Research on radiation carcinogenesis requires a twofold approach. Studies of primary molecular lesions and subsequent cytogenetic changes are essential, but they cannot at present provide numerical estimates of the risk of small doses of ionizing ...
Kellerer, Albrecht M.
core +1 more source
Frontiers in Genetics, 2023 Introduction: The discovery of non-coding RNA (ncRNA) dates back to the pre-genomics era, but the progress in this field is still dynamic and leverages current post-genomics solutions.
Damian Kołat +5 more
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Apoptosis and carcinogenesis [PDF]
British Medical Bulletin, 1997 Many tumours are characterised by increased levels of apoptosis. This observation establishes significance for this process in tumour development, but it does little to elucidate the nature of this role, nor does it yield information relevant to the early stages of carcinogenesis.
S K, Lyons, A R, Clarke
openaire +2 more sources
‐acetylation as a possible contributor to bladder carcinogenesis [PDF]
, 2020 Bladder cancer (BCa) is an exophytic tumor that presents as either noninvasive confined to the mucosa (NMIBC) or invading the detrusor muscle (MIBC), and was recently further subgrouped into molecular subtypes.
Michelle El Kawak +11 more
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EJC Supplements, 2015 Glucocorticoids (GCs) are the most important component of therapy for a number of diseases including combined chemotherapy of hematological malignancies. However, their application is strongly restricted by the development of serious side effects as well
L. Tilova +8 more
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Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium [PDF]
, 2007 Red meat consumption is associated with increased risk of colorectal cancer. We have previously shown that haemin, Hb and red meat promote carcinogen-induced preneoplastic lesions: aberrant crypt foci (ACF) and mucin-depleted foci (MDF) in rats.
Santarelli, Raphaëlle, L. +6 more
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World Journal of Surgical Oncology, 2018 Background M2-polarized macrophages are tumor-associated-macrophages (TAMs), which are important contents of tumor-infiltrating immune cells. Toll-like receptor 4 (TLR4) is a molecular biomarker of tumor aggressiveness and poor prognosis.
Rong-Rong Yao +4 more
doaj +1 more source