Novel and unscrutinized immune entities of the zebrafish gut
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil+5 more
wiley +1 more source
Programa de actividades lógicas para desarrollar el concepto del número en los niños de 5 años de la I.E.I “Felipe Alva y Alva N° 119” Chiclayo [PDF]
Actualmente podemos confrontar altos índices de fracaso en el área de matemática, ante esta realidad los educadores son los llamados a lograr aprendizajes significativos desde edades tempranas.
Odar Sanchez, Milagros Ysabel+1 more
core +1 more source
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona+4 more
wiley +1 more source
El artículo analiza el tratamiento realizado por los diarios La Nación y Página /12 durante una semana a partir del intento de copamiento del cuartel de La Tablada el 23 de enero de 1989.
Javier Torres Molina
doaj
Helping a visually impaired student to improve her social interaction skills at Andrés Bello University, Viña del Mar, Chile : an action research [PDF]
Tesis (Pedagogía en Inglés)During the last decade, inclusion that is “Something which cannot be done to people, it is something in which people are actively involved” (Norwich, 1999), has been used by different educational institutions to define or ...
Aguirre Reyes, Ivette Lissette+3 more
core
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura+8 more
wiley +1 more source
Challenging International Development’s Response to Disability [PDF]
[Excerpt] This article argues that developing countries are often portrayed as being backward in appreciating the importance of inclusion. In addition the stigma attached to disability is thought to be greater in the Developing World.
Bradley, Tamsin
core +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri+5 more
wiley +1 more source
Estudio de pre-factibilidad para una cooperativa de reciclaje y su evaluación económica [PDF]
Trabajo de síntesis aplicadaEl cooperativismo es uno de aquellos elementos que generan tejido social, y que busca también dar solución a problemáticas sociales, tales como inclusión social (ejemplo: recicladores de oficio), contaminación ambiental (bajo ...
Angulo-Castañeda, Wilton+2 more
core
Protein kinase FAM20C—when subcellular localization matters
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source