Results 131 to 140 of about 3,681,465 (347)

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Two Cases of Cytomegalic Inclusion Encephalitis [PDF]

open access: bronze, 1952
A. M. G. Campbell   +2 more
openalex   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

A Scoping Review of Interventions to Promote Diversity, Equity, and Inclusion in the United States Healthcare Workforce

open access: yesJournal of Medical Education and Curricular Development
Background Diversifying the healthcare workforce is critical to achieving a healthier, more equitable society. Objectives The objective of this literature review was to examine and synthesize the literature on interventions to promote diversity, equity ...
Katherine A. Hill   +2 more
doaj   +1 more source

Indigenous Peoples, Land, and Conflict in Mindanao, Philippines

open access: yesAsian Development Review
This paper explores the links between conflict, land, and indigenous peoples on the island of Mindanao in the southern Philippines. The analysis takes advantage of the unprecedented concurrence of data from the 2020 census, an independent conflict data ...
LUCIA MADRIGAL   +2 more
doaj   +1 more source

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