Results 81 to 90 of about 3,681,465 (347)
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Reducing restrictive practices toward individuals with intellectual and developmental disabilities is a globally recognized imperative and human rights priority.
Victoria Sánchez-Gómez+3 more
doaj +1 more source
The rise of digital finance: Financial inclusion or debt trap? [PDF]
Pengpeng Yue+3 more
semanticscholar +1 more source
In this article we claimed that the conception and rhetoric Vygotsky questioned in his works on Defectology still are relevant today in the age of inclusive education. The educational system in several western countries is built upon the strategy of reducing the gap between what the “normal” child can do and the expectations of the disabled child’s ...
Vik, Stine, Somby, Hege Merete
openaire +5 more sources
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Negotiating individual accommodation in higher education
This article discusses ways of understanding the processes involved when disabled students negotiate accessibility in higher education. Despite legislation for universal design and political aims to increase the number of disabled students, individuals ...
Eva Magnus, Jan Tøssebro
doaj +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Publishing the 'Ethnicity Pay Gap' report at Hachette UK – 2019
Hachette UK voluntarily published its first 'Ethnicity Pay Gap' report in April 2019. This article puts the pay gap into the context of Hachette UK’s wider diversity and inclusion agenda and is a key action towards its stated aim to be the publisher of ...
Saskia Bewley
doaj +1 more source