Results 251 to 260 of about 1,278,840 (295)
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Rheumatic Disease Clinics of North America, 1994
IBM remains a poorly understood form of idiopathic inflammatory myopathy, although great progress in the areas of clinical recognition and pathophysiology have been made recently. The question of whether therapy can favorably influence short- and/or long-term outcome is still unanswered.
L H, Calabrese, S M, Chou
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IBM remains a poorly understood form of idiopathic inflammatory myopathy, although great progress in the areas of clinical recognition and pathophysiology have been made recently. The question of whether therapy can favorably influence short- and/or long-term outcome is still unanswered.
L H, Calabrese, S M, Chou
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Continuum, 2022
This article highlights the clinical and diagnostic features of inclusion body myositis (IBM) and provides recent insights into the pathomechanisms and therapeutic strategies of the disease.IBM is an often-misdiagnosed myopathy subtype. Due to the insidious onset and slow progression of muscle weakness, it can often be dismissed as a sign of aging as ...
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This article highlights the clinical and diagnostic features of inclusion body myositis (IBM) and provides recent insights into the pathomechanisms and therapeutic strategies of the disease.IBM is an often-misdiagnosed myopathy subtype. Due to the insidious onset and slow progression of muscle weakness, it can often be dismissed as a sign of aging as ...
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Current Opinion in Neurology, 1999
Sporadic inclusion body myositis is a severely disabling muscle disease that mainly affects elderly individuals. The typical distribution of muscle weakness, poor response to immunosuppressive treatment, pathological accumulation of various proteins in vacuolated muscle fibres, inflammatory reaction and mitochondrial changes have all been subjects of ...
A, Oldfors, C, Lindberg
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Sporadic inclusion body myositis is a severely disabling muscle disease that mainly affects elderly individuals. The typical distribution of muscle weakness, poor response to immunosuppressive treatment, pathological accumulation of various proteins in vacuolated muscle fibres, inflammatory reaction and mitochondrial changes have all been subjects of ...
A, Oldfors, C, Lindberg
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2007
Publisher Summary This chapter discusses inclusion body myositis (IBM). It is usually a slowly progressive myopathy that causes considerable morbidity but does not directly cause mortality. The lack of any effective treatments makes it a challenge to manage.
Michael R, Rose, Robert C, Griggs
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Publisher Summary This chapter discusses inclusion body myositis (IBM). It is usually a slowly progressive myopathy that causes considerable morbidity but does not directly cause mortality. The lack of any effective treatments makes it a challenge to manage.
Michael R, Rose, Robert C, Griggs
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The Journal of Pathology, 1982
AbstractThe clinical and pathological features of two further cases of the condition previously described as Recurring Digital Fibrous Tumour of Childhood are presented. The ultrastructural appearance of the characteristic cell inclusions bears some resemblance to Mallory's hyaline and suggest increased functional activities in the fibroblasts carrying
I M, Zardawi, M J, Earley
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AbstractThe clinical and pathological features of two further cases of the condition previously described as Recurring Digital Fibrous Tumour of Childhood are presented. The ultrastructural appearance of the characteristic cell inclusions bears some resemblance to Mallory's hyaline and suggest increased functional activities in the fibroblasts carrying
I M, Zardawi, M J, Earley
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Current Treatment Options in Neurology, 2000
Inclusion body myositis (IBM) is usually refractory to immunosuppressive therapy; however, a few reports suggest that a minority of patients with IBM may have a partial, transient response or that therapy may slow progression. Therefore, although we generally discourage the use of immunosuppressive therapy for IBM, if the patient is willing to accept ...
, Barohn, , Amato
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Inclusion body myositis (IBM) is usually refractory to immunosuppressive therapy; however, a few reports suggest that a minority of patients with IBM may have a partial, transient response or that therapy may slow progression. Therefore, although we generally discourage the use of immunosuppressive therapy for IBM, if the patient is willing to accept ...
, Barohn, , Amato
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Current Opinion in Rheumatology, 2014
To examine new developments in sporadic inclusion body myositis (IBM), including updated clinical and prognostic factors, novel autoantibody associations, unique histopathologic findings, proposed new clinical diagnostic criteria, and novel therapeutic agents.IBM is a slowly progressive disease, leading to wheelchair use, on average, 12-20 years after ...
Arash H, Lahouti +2 more
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To examine new developments in sporadic inclusion body myositis (IBM), including updated clinical and prognostic factors, novel autoantibody associations, unique histopathologic findings, proposed new clinical diagnostic criteria, and novel therapeutic agents.IBM is a slowly progressive disease, leading to wheelchair use, on average, 12-20 years after ...
Arash H, Lahouti +2 more
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Sporadic Inclusion Body Myositis and Hereditary Inclusion Body Myopathy
Journal of Clinical Neuromuscular Disease, 2002Sporadic inclusion body myositis (s-IBM) is a common but under-recognized myopathy in individuals over 50 years of age. An awareness of the clinical phenotype and of the electrodiagnostic and histopathologic features should lead to improved recognition, and should minimize confusion with polymyositis, motor neuron disease, and other neuromuscular ...
Zachary, Simmons, Javad, Towfighi
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1981
The histochemical and ultrastructural study of muscle biopsies of two patients with a chronic muscle weakness and wasting showed particular changes in muscle fibers: (1) peripheral lined vacuoles, containing whorls of membranes and cytoplasmic debris; (2) collections of intranuclear and intrasarcoplasmic tubular filaments (16-18 nm in external diameter
F M, Tomé +3 more
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The histochemical and ultrastructural study of muscle biopsies of two patients with a chronic muscle weakness and wasting showed particular changes in muscle fibers: (1) peripheral lined vacuoles, containing whorls of membranes and cytoplasmic debris; (2) collections of intranuclear and intrasarcoplasmic tubular filaments (16-18 nm in external diameter
F M, Tomé +3 more
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Tubuloreticular inclusions in inclusion body myositis
Clinical Neuropathology, 2010To evaluate whether patients with inclusion body myositis (IBM) can have tubuloreticular inclusions present in muscle endothelial cells.Light microscopy with histochemical staining and electron microscopy of a right quadriceps muscle biopsy were used to identify the pathological features in an 83-year-old patient with a clinical diagnosis of IBM.Light ...
H D, Katzberg, D G, Munoz
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