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Update on Inclusion Body Myositis
Current Rheumatology Reports, 2018While sporadic inclusion body myositis (sIBM) is the most common acquired muscle disease after age 50, the pathogenesis of this disease is still poorly understood. In this review, we discuss our current state of knowledge in sIBM and provide an update on our current understanding of its pathophysiology and management.Lines of evidence in support of an ...
Duaa, Jabari +3 more
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Hereditary inclusion body myopathies
Current Opinion in Neurology, 1998Hereditary inclusion body myopathies comprise autosomal recessive and autosomal dominant muscle disorders that have a variable clinical phenotype but share similar morphological features. These include rimmed vacuoles within muscle fibres and collections of intrasarcoplasmic and intranuclear tubulofilamentous inclusions, 16-18 nm in external diameter ...
F M, Tomé, M, Fardeau
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Inclusion Body Myositis—A Review
Advances in Anatomic Pathology, 1998Inclusion body myositis (IBM), a sporadic inflammatory myopathy, is the most frequently occurring progressive myopathy in adults older than 55 years. It more commonly affects men and usually is clinically and pathologically distinguishable from dermatomyositis or polymyositis.
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1977
Publisher Summary Inclusion bodies can be simply defined as intracellular structures produced de novo as a result of viral infections. They may contain virus particles, virus-related materials, or ordinary cell constituents in a normal or degenerating condition, either single or, more often, in various proportions.
G P, Martelli, M, Russo
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Publisher Summary Inclusion bodies can be simply defined as intracellular structures produced de novo as a result of viral infections. They may contain virus particles, virus-related materials, or ordinary cell constituents in a normal or degenerating condition, either single or, more often, in various proportions.
G P, Martelli, M, Russo
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Leukocytapheresis in inclusion body myositis
Journal of Clinical Apheresis, 1987AbstractA patient with inclusion body myositis was treated with a course of 22 leukocytaphereses combined with prednisone and azathioprine therapy. He improved clinically during an induction phase of frequent cytapheresis, which reduced the circulating levels of T lymphocytes and monocytes and decreased the ratio of the T4+ to T8+ lymphocyte subsets ...
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Inclusion body myositis: an update
Current Opinion in RheumatologyPurpose of review To review recent advances in our understanding of the epidemiology, pathophysiology, and management of inclusion body myositis (IBM). Recent findings Recent epidemiologic studies have highlighted the morbidity and mortality associated with IBM, including the impact
Nicolaas C, Anderson, Thomas E, Lloyd
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Solid‐State NMR Spectroscopy Reveals that E. coli Inclusion Bodies of HET‐s(218–289) are Amyloids
Angewandte Chemie - International Edition, 2009Christian Wasmer +2 more
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