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Seminars in Neurology, 2012 The idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of rare disorders that share many similarities. In addition to sporadic inclusion body myositis (IBM), these include dermatomyositis, polymyositis, and autoimmune necrotizing myopathy. IBM is the most common IIM after age 50 years.
Richard Barohn, Mazen M Dimachkie
exaly +7 more sources
Obturator hernia associated with inclusion body myositis: a case report [PDF]
Journal of Medical Case ReportsBackground Inclusion body myositis is a progressive muscle disease characterized by weakness, specifically in the flexor digitorum profundus and quadriceps muscles, and commonly affects men over 50 years of age.
Yuma Sato +3 more
doaj +2 more sources
ContinuumThis article addresses the clinical presentation, diagnostic workup, and management of patients with inclusion body myositis (IBM). It also provides an overview of the clinical trial landscape and explores future directions in the pursuit of an effective treatment for the disease.Muscle biopsy remains the cornerstone of the diagnosis, and cytosolic ...
Warman-Chardon, Jodi +2 more
europepmc +6 more sources
Ageing‐Associated Dysregulation of Myogenic Differentiation in Inclusion Body Myositis [PDF]
Journal of Cachexia, Sarcopenia and MuscleSkeletal muscle is a postmitotic tissue dependent on a complex and tightly regulated regeneration process involving numerous intracellular and extracellular factors, including myogenic regulatory factors (MRFs), cytokines and myokines.
Geert M. deVries +2 more
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Proteomic profiles in inclusion body myositis and polymyositis with mitochondrial pathology [PDF]
Acta Neuropathologica CommunicationsBackground Idiopathic inflammatory myopathies (IIMs) are autoimmune muscle diseases with distinct clinical, histopathological, and molecular features. Among them, inclusion body myositis (IBM) is refractory to immunotherapy and characterized by combined ...
Felix Kleefeld +22 more
doaj +2 more sources
Electromyography varies by stage in inclusion body myositis [PDF]
Frontiers in Neurology, 2023 IntroductionInclusion body myositis (IBM) is a chronic inflammatory muscle disease that is characterized by mixed myogenic and neurogenic electromyography (EMG) findings.
Tomoo Mano +7 more
doaj +2 more sources
Mitochondrial defects in sporadic inclusion body myositis—causes and consequences [PDF]
Frontiers in Cell and Developmental BiologySporadic inclusion body myositis (sIBM) is a distinct subcategory of Idiopathic Inflammatory Myopathies (IIM), characterized by unique pathological features such as muscle inflammation, rimmed vacuoles, and protein aggregation within the myofibers ...
Elsie Chit Yu Iu, Ho So, Chi Bun Chan
doaj +2 more sources
Practical Neurology, 2002 Since its delineation in the early 1970s, it has become apparent that inclusion body myositis (IBM) is the most commonly-acquired myopathy in middle-aged and older people. Although classified as one of the inflammatory myopathies, with polymyositis and dermatomyositis, several features set it apart, not least its resistance to immunosuppressant ...
Rabi, Tawil, Robert C, Griggs
openaire +4 more sources
Journal of Rehabilitation Medicine, 2023 Objective: To analyse the association between the daily duration of rehabilitation for inpatients with sporadic inclusion body myositis and improvement in activities of daily living, using a Japanese nationwide inpatient administrative claims database ...
Takuaki Tani +2 more
doaj +1 more source
Clinical types of lung disease in polymyositis and dermatomyositis
Клинический разбор в общей медицине, 2021 The idiopathic inflammatory myopathies are a group of rare, heterogeneous connective tissue disorders characterized by skeletal muscle inflammation. The four main forms of idiopathic inflammatory myopathies are dermatomyositis, polymyositis, inclusion ...
Inna B. Bondarenko +2 more
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