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State of the art microbial recombinant protein production is regularly performed in fed-batch based cultivations. However, these cultivations suffer from highly time-dependent changes in productivity and product quality, leading to high variations in the
Julian Kopp +6 more
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Rift Valley fever phlebovirus (RVFV) causes Rift Valley fever (RVF), an emerging zoonotic disease that causes abortion storms and high mortality rates in young ruminants as well as severe or even lethal complications in a subset of human patients.
Lukas Mathias Michaely +10 more
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Measuring the Implementation of an Ethics Initiative: Child Protection in Scottish Sport [PDF]
Methodologies for measuring the implementation of social inclusion and ethics in sport frequently draw on social marketing techniques or stage models of health behaviour change. This paper illustrates how a composite model of cultural change in sport can
Brackenridge, CH
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Genetics in inclusion body myositis [PDF]
Purpose of review To review the advances in our understanding of the genetics of inclusion body myositis (IBM) in the past year. Recent findings One large genetic association study focusing on immune-related genes in IBM has refined the association within the human leukocyte antigen
Rothwell, Simon +2 more
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Cytomegalovirus-associated esophageal ulcer in an immunocompetent infant: When should ganciclovir be administered? [PDF]
Cytomegalovirus (CMV)-associated esophageal ulcer is rare in immunocompetent infants. The presence of inclusion bodies and immunohistochemical staining for CMV in biopsy specimens obtained during esophagogastroduodenoscopy (EGD) indicate that such ulcers
Ae Suk Kim +11 more
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University Governing Bodies: Reform and Inclusion of External Members [PDF]
Durant els darrers anys s’han publicat un nombre important d’estudis i articles al voltant de la governança de les universitats, el seu sistema de govern i la necessitat d’una reforma en profunditat per tal d’adaptar aquesta institució a les necessitats ...
Lladó Martínez, Albert
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C-Terminal Truncation of α 1,6-Fucosyltransferase from Rhizobium Sp. does not Annul the Transferase Activity of the Enzyme [PDF]
6 pages.-- PMID: 11814863 [PubMed].Recently we have over-expressed the enzyme a 1,6-fucosyltransferase from Rhizobium sp. in Escherichia coli. In this heterologous system the enzyme was mainly expressed as inclusion bodies and the one that was expressed ...
Bastida, Agatha +2 more
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Protein folding and the formation of inclusion bodies
Newly synthesized polypeptide chains must be folded and assembled into unique three-dimensional structures in order to become functionally active. In the folding process, many misfolded proteins maybe produced and thus accumulate as aggregates.
JING Ming-yan, SUN Jian-yi
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Polyglutamine inclusion body toxicity [PDF]
Peer Reviewed ; https://deepblue.lib.umich.edu/bitstream/2027.42/141741/1/mds27226_am.pdf ; https://deepblue.lib.umich.edu/bitstream/2027.42/141741/2/mds27226 ...
openaire +3 more sources
Learning about protein solubility from bacterial inclusion bodies
The progressive solving of the conformation of aggregated proteins and the conceptual understanding of the biology of inclusion bodies in recombinant bacteria is providing exciting insights on protein folding and quality.
García-Fruitós Elena +3 more
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