Results 31 to 40 of about 1,278,840 (295)

Histopathologic bodies: An insight

open access: yesJournal of International Clinical Dental Research Organization, 2011
The histopathological analysis of the tissue includes a detailed study of cellular and nuclear structures and their altered presentation in a given pathology.
Meena Kulkarni   +2 more
doaj   +1 more source

Malakoplakia of the Uterus: A Rare Cause of Postmenopausal Bleeding Mimicking Malignancy [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2019
Malakoplakia is a rare chronic granulomatous disease. It was first reported in 1902 by Michaelis and Gutmann. It may involve any part of the body, most commonly affecting the urinary tract, mainly the urinary bladder.
Chinmoyee Sonowal   +4 more
doaj   +1 more source

Inclusion bodies: a new concept

open access: yesMicrobial Cell Factories, 2010
In the last decades, the understanding of inclusion body biology and consequently, of their properties and potential biotechnological applications have dramatically changed. Therefore, the development of new purification protocols aimed to preserve those
García-Fruitós Elena
doaj   +1 more source

Lafora disease: a case report

open access: yesJournal of Medical Case Reports, 2022
Background Lafora disease is a rare genetic disorder involving glycogen metabolism disorder. It is inherited by autosomal recessive pattern presenting as a progressive myoclonus epilepsy and neurologic deterioration beginning in adolescence.
Naim Zeka   +8 more
doaj   +1 more source

Efficient Autotransporter-Mediated Extracellular Secretion of a Heterologous Recombinant Protein by Escherichia coli

open access: yesMicrobiology Spectrum, 2023
The autotransporter protein secretion system has been used previously to target the secretion of heterologous proteins to the bacterial cell surface and the extracellular milieu at the laboratory scale.
Irene Beriotto   +12 more
doaj   +1 more source

The ubiquitin-proteasome pathway in Huntington's disease. [PDF]

open access: yes, 2008
The accumulation of mutant protein is a common feature of neurodegenerative disease. In Huntington's disease, a polyglutamine expansion in the huntingtin protein triggers neuronal toxicity.
Finkbeiner, Steven, Mitra, Siddhartha
core   +2 more sources

The Biological Potential Hidden in Inclusion Bodies

open access: yesPharmaceutics, 2020
Inclusion bodies (IBs) are protein nanoclusters obtained during recombinant protein production processes, and several studies have demonstrated their potential as biomaterials for therapeutic protein delivery.
Laia Gifre-Renom   +13 more
doaj   +1 more source

Enhanced Production Process of Recombinant Mature Serratiopeptidase in Escherichia coli Using Fed-Batch Culture by Self-Proteolytic Activity of Fusion Protein

open access: yesFermentation, 2022
Microbial enzymes are increasingly finding applications as therapeutics due to their targeted activity and minimal side effects. Serratiopeptidase, also known as a miracle enzyme, has already proved its potential as an anti-inflammatory, mucolytic ...
Pooja Doshi   +6 more
doaj   +1 more source

Gravitational waveforms for spinning compact binaries [PDF]

open access: yes, 2008
The rotation of the bodies and the eccentricity of the orbit have significant effects on the emitted gravitational radiation of binary systems. This work focuses on the evaluation of the gravitational wave polarization states for spinning compact ...
B. Caron   +4 more
core   +2 more sources

Artificial Inclusion Bodies for Clinical Development

open access: yesAdvanced Science, 2020
Bacterial inclusion bodies (IBs) are mechanically stable protein particles in the microscale, which behave as robust, slow‐protein‐releasing amyloids. Upon exposure to cultured cells or upon subcutaneous or intratumor injection, these protein materials ...
Julieta M. Sánchez   +11 more
doaj   +1 more source

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