Results 31 to 40 of about 222,372 (293)
Fermentation, 2022 Microbial enzymes are increasingly finding applications as therapeutics due to their targeted activity and minimal side effects. Serratiopeptidase, also known as a miracle enzyme, has already proved its potential as an anti-inflammatory, mucolytic ...
Pooja Doshi +6 more
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Artificial Inclusion Bodies for Clinical Development
Advanced Science, 2020 Bacterial inclusion bodies (IBs) are mechanically stable protein particles in the microscale, which behave as robust, slow‐protein‐releasing amyloids. Upon exposure to cultured cells or upon subcutaneous or intratumor injection, these protein materials ...
Julieta M. Sánchez +11 more
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Pharmaceutics, 2022 The coordination between histidine-rich peptides and divalent cations supports the formation of nano- and micro-scale protein biomaterials, including toxic and non-toxic functional amyloids, which can be adapted as drug delivery systems.
Julieta María Sánchez +10 more
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Pustulonodular cytomegalovirus infection
Human Pathology: Case Reports, 2020 The cutaneous manifestations of cytomegalovirus (CMV) vary and may be difficult to identify histopathologically. Cutaneous CMV lesions are relatively rare and may be overlooked as infection usually presents in visceral organs, particularly the ...
Mona Deerwester +2 more
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Solubilization of inclusion bodies: insights from explainable machine learning approaches
Frontiers in Chemical Engineering, 2023 We present explainable machine learning approaches for gaining deeper insights into the solubilization processes of inclusion bodies. The machine learning model with the highest prediction accuracy for the protein yield is further evaluated with regard ...
Cornelia Walther +12 more
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Inclusion Bodies in Trachoma [PDF]
British Journal of Ophthalmology, 1955 THE epithelial-cell inclusion, which is characteristically found in the early stages of trachoma was first described by Halberstaedter and Prowazek (1907). Since that time, a considerable literature concerning the nature of these bodies has accumulated.
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Genetics in inclusion body myositis [PDF]
Current Opinion in Rheumatology, 2017 Purpose of review To review the advances in our understanding of the genetics of inclusion body myositis (IBM) in the past year. Recent findings One large genetic association study focusing on immune-related genes in IBM has refined the association within the human leukocyte antigen
Rothwell, Simon +2 more
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Bacterial inclusion bodies are industrially exploitable amyloids. [PDF]
, 2018 Understanding the structure, functionalities and biology of functional amyloids is an issue of emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria during protein production processes, have emerged as unanticipated,
Vázquez Gómez, Esther +16 more
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Tailoring the properties of (catalytically)-active inclusion bodies
Microbial Cell Factories, 2019 Background Immobilization is an appropriate tool to ease the handling and recycling of enzymes in biocatalytic processes and to increase their stability. Most of the established immobilization methods require case-to-case optimization, which is laborious
V. D. Jäger +13 more
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, 2009 This work was supported by the Wellcome Trust.Although the replication cycle of parainfluenza virus type 5 (PIV5) is initially severely impaired in cells in an interferon (IFN)-induced antiviral state, the virus still targets STAT1 for degradation.
Carlos, T S +4 more
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