Results 31 to 40 of about 208,695 (255)

Inclusion Bodies in Trachoma [PDF]

open access: yesBritish Journal of Ophthalmology, 1955
THE epithelial-cell inclusion, which is characteristically found in the early stages of trachoma was first described by Halberstaedter and Prowazek (1907). Since that time, a considerable literature concerning the nature of these bodies has accumulated.
openaire   +2 more sources

Genetics in inclusion body myositis [PDF]

open access: yesCurrent Opinion in Rheumatology, 2017
Purpose of review To review the advances in our understanding of the genetics of inclusion body myositis (IBM) in the past year. Recent findings One large genetic association study focusing on immune-related genes in IBM has refined the association within the human leukocyte antigen
Rothwell, Simon   +2 more
openaire   +3 more sources

Magnetization of active inclusion bodies: comparison with centrifugation in repetitive biotransformations

open access: yesMicrobial Cell Factories, 2018
Background Physiological aggregation of a recombinant enzyme into enzymatically active inclusion bodies could be an excellent strategy to obtain immobilized enzymes for industrial biotransformation processes.
Romana Koszagova   +7 more
doaj   +1 more source

Tailoring the properties of (catalytically)-active inclusion bodies

open access: yesMicrobial Cell Factories, 2019
Background Immobilization is an appropriate tool to ease the handling and recycling of enzymes in biocatalytic processes and to increase their stability. Most of the established immobilization methods require case-to-case optimization, which is laborious
V. D. Jäger   +13 more
doaj   +1 more source

Coiled-Coil Based Inclusion Bodies and Their Potential Applications

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
The production of recombinant proteins using microbial cell factories is frequently associated with the formation of inclusion bodies (IBs). These proteinaceous entities can be sometimes a reservoir of stable and active protein, might display good ...
Marcos Gil-Garcia, Salvador Ventura
doaj   +1 more source

Inclusion Body Myositis

open access: yesContinuum
This article addresses the clinical presentation, diagnostic workup, and management of patients with inclusion body myositis (IBM). It also provides an overview of the clinical trial landscape and explores future directions in the pursuit of an effective treatment for the disease.Muscle biopsy remains the cornerstone of the diagnosis, and cytosolic ...
Warman-Chardon, Jodi   +2 more
openaire   +4 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein Expression

open access: yesCells, 2020
Ebola virus (EBOV) causes severe outbreaks of viral hemorrhagic fever in humans. While virus-host interactions are promising targets for antivirals, there is only limited knowledge regarding the interactions of EBOV with cellular host factors.
Lisa Wendt   +6 more
doaj   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks   +5 more
wiley   +1 more source

Codon Optimization and Chaperone Assisted Solubilization of Recombinant Human Prethrombin-2 Expressed in Escherichia coli

open access: yesMicrobiology Indonesia, 2015
Prethrombin-2 (PT2) is a thrombin precursor, which plays a role in the conversion of fibrinogen into fibrin during blood clotting process. Previous study reported that the expression of human prothrombin-2 (rhPT2) in Escherichia coli formed inclusion ...
SARONOM SILABAN   +6 more
doaj   +1 more source

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