Results 51 to 60 of about 222,372 (293)

Morphological differences between beta2-microglobulin in fibrils and inclusion bodies

, 2011
Over expression of proteins in E. coli frequently results in the production of inclusion bodies. Although ?2-microglobulin frequently forms fibrillar structures, our studies reveal significant differences between the protein in fibrils and inclusion ...
Taylor, Garrick F., Moers, Karsten, Philip T. F. Williamson, Karsten Mörs, Clemens Glaubitz, Stephen P. Wood, Werner, Jorn M., Wood, Stephen P., Williamson, Philip T. F., Garrick F. Taylor, Williamson, Phillip T.F., Mörs, Karsten, Glaubitz, Clemens, Jörn M. Werner   +13 more
core   +1 more source

Small surfactant-like peptides can drive soluble proteins into active aggregates

Microbial Cell Factories, 2012
Background Inactive protein inclusion bodies occur commonly in Escherichia coli (E. coli) cells expressing heterologous proteins. Previously several independent groups have found that active protein aggregates or pseudo inclusion bodies can be induced by
Zhou Bihong, Xing Lei, Wu Wei, Zhang Xian-En, Lin Zhanglin   +4 more
doaj   +1 more source

Studies on the Structure and Properties of Membrane Phospholipase A₁ Inclusion Bodies Formed at Low Growth Temperatures Using GFP Fusion Strategy

Molecules, 2021
The effect of cultivation temperatures (37, 26, and 18 °C) on the conformational quality of Yersinia pseudotuberculosis phospholipase A1 (PldA) in inclusion bodies (IBs) was studied using green fluorescent protein (GFP) as a folding reporter.
Svetlana I. Bakholdina, Anna M. Stenkova, Evgenia P. Bystritskaya, Evgeniy V. Sidorin, Natalya Yu. Kim, Ekaterina S. Menchinskaya, Tatiana Yu. Gorpenchenko, Dmitry L. Aminin, Nikita A. Shved, Tamara F. Solov’eva   +9 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Inclusion measures of convex bodies (II)

, 2007
In this paper, several inequalities for inclusion measures of convex bodies were obtained. The inclusion measure was proved to have concavity by considering the property of relative inner parallel body.
Xiong, G, Cheung, WS
core   +1 more source

Update in inclusion body myositis [PDF]

Current Opinion in Rheumatology, 2013
The purpose of this study is to review recent scientific advances relating to the natural history, cause, treatment and serum and imaging biomarkers of inclusion body myositis (IBM).Several theories regarding the aetiopathogenesis of IBM are being explored and new therapeutic approaches are being investigated. New diagnostic criteria have been proposed,
Machado, P, Brady, S, Hanna, MG
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Renal Involvement in Congenital Cytomegalovirus Infection: A Systematic Review

Microorganisms, 2021
Background: Congenital cytomegalovirus (cCMV) infection is the most frequent mother-to-child transmitted infection worldwide and a prevalent cause of neonatal disease and long-term morbidity.
María Ríos-Barnés, Clàudia Fortuny, Ana Alarcón, Antoni Noguera-Julian   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source