Results 21 to 30 of about 208,695 (255)
Journal of Medical Case Reports, 2022 Background Lafora disease is a rare genetic disorder involving glycogen metabolism disorder. It is inherited by autosomal recessive pattern presenting as a progressive myoclonus epilepsy and neurologic deterioration beginning in adolescence.
Naim Zeka +8 more
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Microbiology Spectrum, 2023 The autotransporter protein secretion system has been used previously to target the secretion of heterologous proteins to the bacterial cell surface and the extracellular milieu at the laboratory scale.
Irene Beriotto +12 more
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Schaumann bodies: The basophilic inclusion body
Journal of Oral and Maxillofacial Pathology, 2023 Schaumann bodies are the inclusion bodies usually seen in sarcoidosis, but can also be found in other conditions like tuberculosis, chronic beryllium diseases and Crohn’s diseases. Histopathologically, these bodies appear as round to oval shell-like basophilic calcifications usually considered to be as a residuum of lysosomal organelles activity.
Jain, Ankush P. +3 more
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Artificial Inclusion Bodies for Clinical Development
Advanced Science, 2020 Bacterial inclusion bodies (IBs) are mechanically stable protein particles in the microscale, which behave as robust, slow‐protein‐releasing amyloids. Upon exposure to cultured cells or upon subcutaneous or intratumor injection, these protein materials ...
Julieta M. Sánchez +11 more
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The Biological Potential Hidden in Inclusion Bodies
Pharmaceutics, 2020 Inclusion bodies (IBs) are protein nanoclusters obtained during recombinant protein production processes, and several studies have demonstrated their potential as biomaterials for therapeutic protein delivery.
Laia Gifre-Renom +13 more
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Fermentation, 2022 Microbial enzymes are increasingly finding applications as therapeutics due to their targeted activity and minimal side effects. Serratiopeptidase, also known as a miracle enzyme, has already proved its potential as an anti-inflammatory, mucolytic ...
Pooja Doshi +6 more
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Pharmaceutics, 2022 The coordination between histidine-rich peptides and divalent cations supports the formation of nano- and micro-scale protein biomaterials, including toxic and non-toxic functional amyloids, which can be adapted as drug delivery systems.
Julieta María Sánchez +10 more
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Isolation of cell-free bacterial inclusion bodies
Microbial Cell Factories, 2010 Background Bacterial inclusion bodies are submicron protein clusters usually found in recombinant bacteria that have been traditionally considered as undesirable products from protein production processes.
Rodríguez-Carmona Escarlata +4 more
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Pustulonodular cytomegalovirus infection
Human Pathology: Case Reports, 2020 The cutaneous manifestations of cytomegalovirus (CMV) vary and may be difficult to identify histopathologically. Cutaneous CMV lesions are relatively rare and may be overlooked as infection usually presents in visceral organs, particularly the ...
Mona Deerwester +2 more
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Solubilization of inclusion bodies: insights from explainable machine learning approaches
Frontiers in Chemical Engineering, 2023 We present explainable machine learning approaches for gaining deeper insights into the solubilization processes of inclusion bodies. The machine learning model with the highest prediction accuracy for the protein yield is further evaluated with regard ...
Cornelia Walther +12 more
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