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Inclusion Bodies in Ionic Liquids [PDF]
The pivotal role of proteins in pharmaceuticals is challenged by stability issues, making the study of inclusion bodies—a source of insoluble protein aggregates—increasingly relevant.
András Szabadi +3 more
doaj +3 more sources
Bacterial inclusion bodies contain amyloid-like structure. [PDF]
Protein aggregation is a process in which identical proteins self-associate into imperfectly ordered macroscopic entities. Such aggregates are generally classified as amorphous, lacking any long-range order, or highly ordered fibrils. Protein fibrils can
Lei Wang +4 more
doaj +2 more sources
Isolation of cell-free bacterial inclusion bodies [PDF]
Background Bacterial inclusion bodies are submicron protein clusters usually found in recombinant bacteria that have been traditionally considered as undesirable products from protein production processes.
Rodríguez-Carmona Escarlata +4 more
doaj +2 more sources
Background Physiological aggregation of a recombinant enzyme into enzymatically active inclusion bodies could be an excellent strategy to obtain immobilized enzymes for industrial biotransformation processes.
Romana Koszagova +7 more
doaj +2 more sources
Lewy and his inclusion bodies: Discovery and rejection
Fritz Jacob Heinrich Lewy described the pathology of Paralysis agitans [Parkinson disease] and was the first to identify eosinophilic inclusion bodies in neurons of certain brain nuclei, later known as Lewy bodies, the pathological signature of the Lewy ...
Eliasz Engelhardt +1 more
doaj +3 more sources
Toxicity Profiling of Bacterial Inclusion Bodies in Human Caco-2 Cells. [PDF]
Raw data collected directly from a primary source and has not been processed in any way to address the hypothesis of the potential tocicity of Inclusion bodies (IBs) obtained from different prokaryotic ...
Barguilla I +6 more
europepmc +3 more sources
The idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of rare disorders that share many similarities. In addition to sporadic inclusion body myositis (IBM), these include dermatomyositis, polymyositis, and autoimmune necrotizing myopathy. IBM is the most common IIM after age 50 years.
Mazen M, Dimachkie, Richard J, Barohn
openaire +5 more sources
Sporadic inclusion body myositis (sIBM) is a poorly understood immune and degenerative disease of skeletal muscle. Here, current opinion of the nature of this disease is summarized.Recent findings for sIBM include further characterization of muscle involvement through magnetic resonance imaging, the role of muscle as a host for immune cells, progress ...
Ivanidze, Jana +5 more
openaire +5 more sources
Coiled-coil inspired functional inclusion bodies
Background Recombinant protein expression in bacteria often leads to the formation of intracellular insoluble protein deposits, a major bottleneck for the production of soluble and active products.
Marcos Gil-Garcia +2 more
doaj +1 more source
Kinetics of inclusion body formation and its correlation with the characteristics of protein aggregates in Escherichia coli. [PDF]
The objective of the research was to understand the structural determinants governing protein aggregation into inclusion bodies during expression of recombinant proteins in Escherichia coli.
Arun K Upadhyay +3 more
doaj +1 more source

