Results 11 to 20 of about 1,278,840 (295)

State-of-the-art and novel approaches to mild solubilization of inclusion bodies [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Throughout the twenty-first century, the view on inclusion bodies (IBs) has shifted from undesired by-products towards a targeted production strategy for recombinant proteins.
Robert Klausser   +11 more
doaj   +2 more sources

Morphogenesis and functional organization of viral inclusion bodies [PDF]

open access: yesCell Insight, 2023
Eukaryotic viruses are obligate intracellular parasites that rely on the host cell machinery to carry out their replication cycle. This complex process involves a series of steps, starting with virus entry, followed by genome replication, and ending with
Zhifei Li   +4 more
doaj   +2 more sources

Two Cases of Feather Dystrophy in Free-Living Griffon Vultures (Gyps fulvus fulvus) Associated with Viral-like Inclusion Bodies [PDF]

open access: yesAnimals
The griffon vulture (Gyps fulvus fulvus) is a scavenger species that plays a vital ecological role in carrion removal. Successful survival and reproduction in captive and wildlife conditions require optimal physical status and plumage integrity ...
Stefano Pesaro   +12 more
doaj   +2 more sources

Inclusion bodies: Not that bad… [PDF]

open access: yesFrontiers in Microbiology, 2014
The formation of inclusion bodies constitute a frequent event during the production of heterologous proteins in bacterial hosts. Although the mechanisms leading to their formation are not completely understood, empirical data have been exploited trying ...
Ana eRamon   +2 more
doaj   +3 more sources

Neurodegenerative disease-associated inclusion bodies are cleared by selective autophagy in budding yeast [PDF]

open access: yesAutophagy Reports, 2023
Protein misfolding, aggregation, and accumulation cause neurodegenerative disorders. One such disorder, Huntington’s disease, is caused by an increased number of glutamine-encoding trinucleotide repeats CAG in the first exon of the huntingtin (HTT) gene.
Austin Folger   +4 more
doaj   +2 more sources

Neuroserpin Inclusion Bodies in a FENIB Yeast Model [PDF]

open access: yesMicroorganisms, 2021
FENIB (familial encephalopathy with neuroserpin inclusion bodies) is a human monogenic disease caused by point mutations in the SERPINI1 gene, characterized by the intracellular deposition of polymers of neuroserpin (NS), which leads to proteotoxicity ...
Valentina Vapore   +9 more
doaj   +2 more sources

Coiled-Coil Based Inclusion Bodies and Their Potential Applications [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
The production of recombinant proteins using microbial cell factories is frequently associated with the formation of inclusion bodies (IBs). These proteinaceous entities can be sometimes a reservoir of stable and active protein, might display good ...
Marcos Gil-Garcia, Salvador Ventura
doaj   +2 more sources

Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids [PDF]

open access: yeseLife
Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs).
Xiuling Cao   +9 more
doaj   +2 more sources

A compendium of specific histopathological bodies in dermatology

open access: yesIndian Journal of Dermatology, 2021
The spectrum of histopathological variations of most of the Dermatological conditions is so wide and overlapping that even with our current vast knowledge of this discipline, it seems to be a tough task for clinicians as well as Dermatopathologists to ...
Anup Kumar Tiwary   +3 more
doaj   +1 more source

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