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Inclusion body myositis

Current Opinion in Rheumatology, 2011
Sporadic inclusion body myositis (sIBM) is a poorly understood immune and degenerative disease of skeletal muscle. Here, current opinion of the nature of this disease is summarized.Recent findings for sIBM include further characterization of muscle involvement through magnetic resonance imaging, the role of muscle as a host for immune cells, progress ...
Ivanidze, Jana, Hoffmann, Reinhard, Lochmüller, Hanns, Engel, Andrew G., Hohlfeld, Reinhard, Dornmair, Klaus   +5 more
  +7 more sources

Clinical types of lung disease in polymyositis and dermatomyositis

Клинический разбор в общей медицине, 2021
The idiopathic inflammatory myopathies are a group of rare, heterogeneous connective tissue disorders characterized by skeletal muscle inflammation. The four main forms of idiopathic inflammatory myopathies are dermatomyositis, polymyositis, inclusion ...
Inna B. Bondarenko, Liubov A. Ponomareva, Elena N. Popova   +2 more
doaj   +1 more source

Muscle Imaging in Inclusion Body Myositis: Refinement of MRI Criteria and Insights Into Upper Body Involvement. [PDF]

J Cachexia Sarcopenia Muscle
ABSTRACT Background The diagnosis of inclusion body myositis (IBM) can be delayed because of its heterogeneous clinical presentation and the lack of specific biomarkers. Muscle imaging has gained increasing relevance over the past decade and is now included among the supportive criteria in the international diagnostic guidelines.
Torchia E, Lucchini M, Verdu-Diaz J, Bortolani S, Ravera B, Carlomagno V, Cicia A, Bernardo D, Monforte M, Rehmann R, Kley RA, Sabatelli M, Díaz-Manera J, Ricci E, Mirabella M, Tasca G.   +15 more
europepmc   +2 more sources

The myokine GDF-15 is a potential biomarker for myositis and associates with the protein aggregates of sporadic inclusion body myositis. [PDF]

, 2020
Background: The cytokine growth differentiation factor-15 (GDF-15) has been associated with inflammatory and mitochondrial disease, warranting exploration of its expression in myositis patients.
De Bleecker, Jan, De Paepe, Boel, Verhamme, Fien   +2 more
core   +2 more sources

Genetics in inclusion body myositis [PDF]

Current Opinion in Rheumatology, 2017
Purpose of review To review the advances in our understanding of the genetics of inclusion body myositis (IBM) in the past year. Recent findings One large genetic association study focusing on immune-related genes in IBM has refined the association within the human leukocyte antigen
Rothwell, Simon, Lilleker, James, Lamb, Janine   +2 more
openaire   +3 more sources

Treatment for inclusion body myositis [PDF]

, 2015
Background Inclusion body myositis (IBM) is a late-onset inflammatory muscle disease (myopathy) associated with progressive proximal and distal limb muscle atrophy and weakness.
Brassington, Ruth, Dalakas, Marinos, Griggs, Robert, Jones, Katherine, Leong, Kevin, Miller, James, Rose, Michael R., Walter, Maggie C.   +7 more
core   +2 more sources

Sporadic inclusion body myositis in the rheumatology clinic

Indian Journal of Rheumatology, 2020
Sporadic inclusion body myositis (sIBM) is a progressive and insidious skeletal muscle disorder characterized classically by the quadriceps, wrist, and finger flexor weakness.
Fernando Henrique Carlos de Souza, Gustavo Luiz Behrens Pinto, Jean Marcos de Souza, Pablo Arturo Olivo Pallo, Leonardo Santos Hoff, Samuel Katsuyuki Shinjo   +5 more
doaj   +1 more source

A Rare Case of Sporadic Inclusion Body Myositis (s-IBM) [PDF]

Journal of Clinical and Diagnostic Research, 2016
Sporadic inclusion body myositis (s-IBM) is an acquired inflammatory myopathy. Clinical presentation is variable. The usual presentation is progressive weakness and atrophy of the arms and leg muscles, especially of the quadriceps femoris which is ...
Sourya Acharya, Samarth Shukla, Pritum Kitey, Shameem Khan, SN Mahajan   +4 more
doaj   +1 more source

Inclusion body myositis: therapeutic approaches. [PDF]

, 2012
The idiopathic inflammatory myopathies are a heterogeneous group of diseases that include dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM) and other less common myopathies.
Aggarwal, Rohit, Oddis, Chester V
core   +1 more source

Inclusion Body Myositis Treated with Alemtuzumab

European Journal of Case Reports in Internal Medicine, 2019
Inclusion body myositis (IBM) is a chronic inflammatory myopathy with a progressive course. It is more common in the later years of life and usually presents with limb weakness.
Juliana Sá, João Costelha, Antonio Marinho   +2 more
doaj   +1 more source