Results 21 to 30 of about 15,592 (224)

Inflammatory Muscle Diseases. [PDF]

, 2015
INFLAMMATORY MYOPATHIES ARE THE LARGEST GROUP OF POTENTIALLY treatable myopathies in children and adults. They constitute a heterogeneous group of disorders that are best classified, on the basis of distinct clinicopathologic features, in four subtypes ...
Dalakas, Marinos
core   +3 more sources

BLOOD FLOW RESTRICTED RESISTANCE TRAINING ATTENUATES MYOSTATIN GENE EXPRESSION IN A PATIENT WITH INCLUSION BODY MYOSITIS

Biology of Sport, 2014
Inclusion body myositis is a rare idiopathic inflammatory myopathy that produces extreme muscle weakness. Blood flow restricted resistance training has been shown to improve muscle strength and muscle hypertrophy in inclusion body myositis.
A.R. Santos, M.T. Neves Jr., B. Gualano, G.C. Laurentino, A.H. Lancha Jr, C. Ugrinowitsch, F.R. Lima, M.S. Aoki   +7 more
doaj   +1 more source

Dysphagia as the Presenting Symptom for Inclusion Body Myositis

Journal of Investigative Medicine High Impact Case Reports, 2021
Dysphagia can be one of the manifestations of inflammatory myopathies (IMs). In some patients, it can be one of the presenting symptoms or the only symptom.
Marcus Juan Esteban MD, Darine Kassar MD, Osvaldo Padilla MD, MPH, Richard McCallum MD   +3 more
doaj   +1 more source

[Inclusion body myositis]. [PDF]

Presse medicale (Paris, France : 1983), 1996
Inclusion body myositis has been recently recognized as a clinical entity although its exact definition remains uncertain. Initially considered to be an inflammatory dermatomyositis, inclusion body myositis can actually take on three specific forms: disseminated muscle atrophy and weakness, pseudopolymyositis, or pseudo-degenerative disease.
Garlepp, M.J., Mastaglia, F.L.
openaire   +4 more sources

MRI biomarker assessment of neuromuscular disease progression: a prospective observational cohort study [PDF]

, 2015
BACKGROUND: A substantial impediment to progress in trials of new therapies in neuromuscular disorders is the absence of responsive outcome measures that correlate with patient functional deficits and are sensitive to early disease processes ...
Fischmann, A, Hanna, MG, Machado, PM, Morrow, JM, Reilly, MM, Sinclair, CD, Thornton, JS, Yousry, TA   +7 more
core   +1 more source

The effects of an intronic polymorphism in TOMM40 and APOE genotypes in sporadic inclusion body myositis. [PDF]

, 2015
A previous study showed that, in carriers of the apolipoprotein E (APOE) genotype ε3/ε3 or ε3/ε4, the presence of a very long (VL) polyT repeat allele in "translocase of outer mitochondrial membrane 40" (TOMM40) was less frequent in patients with ...
Barohn, R.J., Bettencourt, C., Brady, S., De Bleecker, J., De Paepe, B., Dimachkie, M.M., Fox, Z., Gang, Q., Hanna, M.G., Healy, E., Hilton-Jones, D., Holton, J.L., Houlden, H., Machado, P.M., Mantegazza, R., Mastaglia, F., Moggio, M., Mora, M., Needham, M., Parton, M., Ripolone, M., Shaibani, A., Shieh, P.B., Violano, R., Zanoteli, E., Zanotti, S.   +25 more
core   +1 more source

Pembrolizumab on pre-existing inclusion body myositis: a case report

BMC Rheumatology, 2020
Background Cases of exacerbation of pre-existing neuromuscular diseases induced by immune checkpoint inhibitors (ICIs) have rarely been reported because patients with autoimmune diseases have generally been excluded from ICI therapy due to the increased ...
Naohiro Uchio, Atsushi Unuma, Toshiyuki Kakumoto, Masao Osaki, Yoshitaka Zenke, Kenichi Sakuta, Akatsuki Kubota, Yoshikazu Uesaka, Tatsushi Toda, Jun Shimizu   +9 more
doaj   +1 more source

Phenotypical statin‐associated immune‐mediated necrotizing myositis with histological features of inclusion body myositis

Rheumatology & Autoimmunity, 2023
Introduction Statin‐associated immune‐mediated necrotizing myositis (IMNM) is a rare but distinct idiopathic inflammatory myopathy (IIM) that requires early recognition and intervention to prevent irreversible muscle damage. It is typically characterized
Nicole Daver, Sara Tonini
doaj   +1 more source

Inclusion body myositis: Update on the diagnostic and therapeutic landscape

Frontiers in Neurology, 2022
Inclusion body myositis (IBM) is a progressive muscle disease affecting patients over the age of 40, with distinctive clinical and histopathological features. The typical clinical phenotype is characterized by prominent involvement of deep finger flexors
Elie Naddaf
doaj   +1 more source

A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years' experience; the Juvenile Dermatomyositis National (UK and Ireland) Cohort Biomarker Study and Repository for Idiopathic Inflammatory Myopathies [PDF]

, 2011
Objectives: The paediatric idiopathic inflammatory myopathies (IIMs) are a group of rare chronic inflammatory disorders of childhood, affecting muscle, skin and other organs.
Bohan, Bohan, Brown, Chinoy, Chinoy, Christen-Zaech, Clarissa A. Pilkington, Constantin, Elst, Gunawardena, Gunawardena, Huber, Huber, Huber, Huber, Isenberg, Joyce E. Davidson, Kevin Murray, Kim, Li, Li, Lovell, Lowry, Lucy R. Wedderburn, Maillard, Maillard, Marhaug, McCann, McCann, McCann, Mendez, Miller, Neil Martin, Pachman, Pachman, Petra Krol, Ravelli, Rider, Rider, Rider, Rider, Riley, Riley, Sally Smith, Salomonsson, Stringer, Symmons, Varsani, Wedderburn, Wedderburn, Wedderburn   +50 more
core   +1 more source