Results 211 to 220 of about 1,877,147 (362)

Effect of Metallurgical Process on Rotational Bending Fatigue Properties of H13 Hot Work Die Steel. [PDF]

Materials (Basel)
Li Y, Ma D, Zhang S, Sun X, Li Y, Zhang Z, Zhong Z.   +6 more
europepmc   +1 more source

Health Digital Inclusion and Patient-centered Care Readiness in the USA

, 2013
Jun Sun, Ying Wang, Néstor Rodríguez
openalex   +2 more sources

Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

Proceedings of the National Academy of Sciences of the United States of America, 2009
Kelvin C. Luk, Cheng Song, Patrick O’Brien, Anna M. Stieber, Jonathan R. Branch, K. Brunden, J. Trojanowski, V. Lee   +7 more
semanticscholar   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

HDAC6 Inhibition Reduces Seeded Tau and α-Synuclein Pathologies in Primary Neuron Cultures and Wild-Type Mice. [PDF]

J Neurosci
Crowe A, Yao Y, Newman M, Hoxha K, Baffic T, Brunden KR.   +5 more
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Synphilin-1 modulates alpha-synuclein assembly, release and uptake. [PDF]

NPJ Parkinsons Dis
Lázaro DF, Amen T, Gerhardt E, Song C, Burns R, Kruse N, Santos PI, Milovanovic D, Höglinger G, Mollenhauer B, Luk KC, Lee VM, Outeiro TF.   +12 more
europepmc   +1 more source

Beyond inclusion

The energy sector often reduces feminisms to the inclusion of women or instrumentalizes Women’s Day or LGBTQIA+ pride to assert its ‘feminist’ nature. This chapter argues that advocating for a feminist understanding of energy justice goes beyond inclusion and washing practices, calling for substantive, systemic change.
openaire   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Triple-negative complementary metamaterial for ultrasound transmission through elastic barrier. [PDF]

Sci Rep
Lee KY, Jeon W.
europepmc   +1 more source