Results 111 to 120 of about 702,644 (319)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Teacher Educators' and Pre-service Teachers' Attitudes, Knowledge and Understanding on Special Education and Inclusive Education in the Solomon Islands.

open access: yes, 2008
Since the merging of special education and regular mainstream education into a unified system now known as inclusive education, this concept has kept many educators divided. However, it appears that inclusive education has now become the preferred option
Simi, Janine
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Inclusive Development: Two Papers on Conceptualization, Application, and the ADB Perspective

open access: yes
This compendium brings together two companion papers on inclusive development. The first paper uses the global literature to formulate a conceptualisation of inclusive development and inclusive growth, and to put the conceptualisation through its paces ...
Rauniyar, Ganesh P., Kanbur, Ravi
core  

Inclusive design for air travel

open access: yes, 2009
(Inclusive design in air travel by baird L and Dong H) This paper addresses the issue of inclusive design in air travel. Firstly the scale of the problem is defined with reference to passenger demographics, and the different stages of a typical ...
Baird, L, Dong, H
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Office of Inclusive Excellence Newsletter

open access: yes, 2020
Georgia Southern Inclusive Excellence Action ...
Georgia Southern University, Office of Inclusive Excellence
core  

Is the use of the investment resources allocated to municipalities in Cameroon efficient?

open access: yesPublic Sector Economics
The aim of this study is to assess the technical efficiency of the use of investment resources allocated to municipalities in Cameroon. The data used come from the Special Inter-municipal Equipment and Intervention Fund (FEICOM), the National ...
Sylvain Ngô Ndjang   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Teachers' views on providing for children with special needs in inclusive classrooms:a papua new guinea study

open access: yes, 2006
The purpose of having inclusive education is to value children with special needs so they can participate equally in all educational activities alongside their peers without special needs.
Mapsea, Allan Jim
core  

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