Results 171 to 180 of about 1,231,942 (313)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

A value hierarchy for inclusive design of heart valve implants in regenerative medicine. [PDF]

Regen Med
De Kanter AJ, Daal MV, Gunn CJ, Bredenoord AL, Graeff N, Jongsma KR.   +5 more
europepmc   +1 more source

TOPICS IN INCLUSIVE DESIGN FOR THE GRADUATE HUMAN FACTORS ENGINEERING CURRICULUM. [PDF]

Proc Hum Factors Ergon Soc Annu Meet, 2017
D'Souza C.
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Inclusive design and usability testing: Involving an end-user in developing augmentative and alternative communication user interfaces using an open-source platform. [PDF]

J Rehabil Assist Technol Eng
Benson-Goldberg S, Geist L, Erickson K.
europepmc   +1 more source

Understanding influences on the uptake of pulmonary rehabilitation in the East of England: an Inclusive Design/mixed-methods study protocol. [PDF]

BMJ Open, 2018
Liu Y, Dickerson T, Early F, Fuld J, Clarkson PJ.   +4 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Watch Your Back, Girl! On the Transformative Impact of COVID Narratives at a Time of Crisis

On_Culture, 2021
Kamila Iżykowicz
doaj   +1 more source

Community-based, inclusive design of a 3D tactile map to enable playground navigation for children who are visually impaired and blind. [PDF]

J Rehabil Assist Technol Eng
Alturaifi A, Colbert J, Doakes L, Dupont K, Faulk B, Gatune E, Gaudet J, Gayle A, Jena S, Kennard G, Le T, Lima M, Maxwell I, Matherne C, Robinson JF, Tramontana B, Tran T, Vallery S.   +17 more
europepmc   +1 more source