Results 121 to 130 of about 1,705,843 (309)

Special Education in Catholic Schools Viewed from a Liberatory Hermeneutic [PDF]

, 2019
This study explores anew the issue of providing special education in Catholic schools by viewing the ethical implications from a liberatory hermeneutic.
Carlson, Mary E., LaBelle, Jeffrey
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Their voices matter: student and professional perspectives on overcoming school attendance problems in the context of social, emotional, and behavioral difficulties

Frontiers in Education
School attendance problems (SAPs) are a growing concern worldwide, particularly among students with social, emotional, and behavioral difficulties (SEBD), who are at elevated risk of school-related stress and disengagement.
Chiara Enderle, Chiara Enderle, Louisa Kotschy, Heinrich Ricking, Susanne Kreitz-Sandberg   +4 more
doaj   +1 more source

The impact of curriculum content in fostering inclusive engineering: data from a national evaluation of the use of EWB projects in first year engineering [PDF]

, 2011
The year of Humanitarian Engineering draws our attention to the need to develop engineers who are not just technically competent but who can effectively address the needs of communities, maintain their ethical responsibilities, and take sustainability ...
Brodie, Lyn, Buys, Laurie, Crosthwaite, Caroline, Jolly, Lesley, Kavanagh, Lydia   +4 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The Inclusive Growth and Development Report 2017 [PDF]

, 2017
Around the globe, leaders of governments and other stakeholder institutions enter 2017 facing a set of difficult and increasingly urgent questions:With fiscal space limited, interest rates near zero, and demographic trends unfavorable in many countries ...
Gemma Corrigan, Jennifer Blanke, Margareta Drzeniek Hanouz, Richard Samans   +3 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Exploring corporate social responsibility practices in the telecommunications, broadcasting and courier sectors: a comparative industry analysis

Humanities & Social Sciences Communications
This study aims to dissect and understand the Corporate Social Responsibility (CSR) endeavours of organisations within Malaysia’s telecommunications, broadcasting, postal and courier services sectors, particularly those holding licenses from the ...
Naziatul Aziah Mohd Radzi, Normaizatul Akma Saidi, Suziana Hassan, Mohamad Syahrul Nizam Ibrahim, Khai Ern Lee   +4 more
doaj   +1 more source