Results 241 to 250 of about 1,705,843 (309)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

FunEball: an emerging inclusive sport to enhance engagement and fundamental movement skills in physical education. [PDF]

Front Psychol
Liu Q, Dong Q, Fang Q, Oh E, Jia M, Yang D.   +5 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Research on the path of high-quality development of the smart health and aging care industry driven by digital economy- dynamic QCA analysis based on TOE framework. [PDF]

Front Public Health
Tan X, Shu X.
europepmc   +1 more source

Advancing Inclusive Design Practice for Queer Youth Using Digital Technologies for Mental Health. [PDF]

Med J Aust
Poulsen A, Hickie IB, Hockey SJ, Iorfino F, LaMonica HM.   +4 more
europepmc   +1 more source

Strengthening Undergraduate Medical Education for Inclusive Health Care for People With Down Syndrome and Intellectual and Developmental Disabilities in Medical Schools: Protocol for a Scoping Review.

JMIR Res Protoc
Amaral de Almeida Bistafa I, Antonio Ribeiro Filho M, Dos Santos Costa AC, Pimenta Saad AF, Ferreira Franco R, Aparecida de Sales Floriano J, Roberto Dos Santos E, de Souza Menezes JD, Querino da Silva M, Nunes Longhi Aleixo D, Fazuoli Chubaci E, Karina Stefani A, Donegá Martinez W, Belchior da Silveira Junior P, Mirtes Zecchin A, Gonçalves Cristóvão NB, Bertolazzo Quitério A, Mendonça Ribeiro R, Cristina Móz Vaz Oliani D, Hélio Oliani A, Alahmar Bianchin M, Cesar Fava Spessoto L, Helú Mendonça Ribeiro RC, César André J.   +23 more
europepmc   +1 more source

The impact of digital collaboration tools on inclusive leadership in multicultural teams in the context of global remote work: a psychological perspective on empathy, cohesion, and cross cultural communication. [PDF]

Front Psychol
Yang X, Wang Y.
europepmc   +1 more source

Design considerations for miniaturized biosensor-enabled systems for older adults: insights from participatory design. [PDF]

Front Bioeng Biotechnol
Quidato M, Suarez MT, Ebardo R.
europepmc   +1 more source

Strengthening equitable research capacity in response to infectious diseases of poverty. [PDF]

BMJ Glob Health
Asampong E, Echavarria Mejia MI, Mahendradhata Y, Vahedi M, Thorson A.   +4 more
europepmc   +1 more source

Defining the guiding principles of weight-inclusive nutrition education. [PDF]

Front Public Health
Levinson JA, Gamble J, Rose K, Garnett BR, Hinchey D, Pope L.   +5 more
europepmc   +1 more source