Results 131 to 140 of about 6,627,008 (361)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The Ethic of Care and Inclusive Education

open access: yes, 2018
This article deals with the ethic of care in education, with a specific focus on classrooms that include students with disabilities. After a brief overview of historical and legal issues which led to the inclusive education movement, the discussion ...
Anderson, David W.
core  

Implementasi Penyelenggaraan Pendidikan Inklusif Bagi Anak Berkebutuhan Khusus (ABK) dalam Lingkup Sekolah Inklusi (Studi Kasus: SD No. 11 Jimbaran) [PDF]

open access: yes, 2017
Inclusive education is an educational service system that provides opportunities for all children to study together in a public school with attention to diversity and individual needs.
Wijayanti, A. A. (A)
core  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Using Theory-Based Test Construction to Develop a New Curriculum-Based Measurement for Sentence Reading Comprehension

open access: yesFrontiers in Education, 2018
Reading comprehension at sentence level is a core component in the students' comprehension development, but there is a lack of comprehension assessments at the sentence level, which respect the theory of reading comprehension.
Jana Jungjohann   +3 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Evaluasi Kebijakan Penyelenggaraan Pendidikan Inklusif Tingkat Sekolah Dasar di Kecamatan Koja Jakarta Utara (Studi pada Sdn Tugu Utara 11) [PDF]

open access: yes, 2017
In Indonesia, everyone has the right to education including children with disabilities. Indonesian Government established a regulation related to this matter which is Inclusive Education Policy.
Fasha, A. F. (Azizah)   +1 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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