Results 151 to 160 of about 19,298,628 (337)

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

open access: yesAdvanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou   +8 more
wiley   +1 more source

LEVEL OF INCOME OF POPULATION: THE CURRENT STATE AND PERSPECTIVES [PDF]

open access: yes, 2000
Glauche, Michael   +2 more
core   +1 more source

Impacts of Population and Income Growth Rates on Threatened Mammals and Birds [PDF]

open access: yes
Per capita income and human population levels in a country have direct influences on its environmental outcomes. Countries with same level of income may have different rate of income growth and vice versa, suggesting that the influence of the rate of ...
Laband, David N., Pandit, Ram
core   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang   +8 more
wiley   +1 more source

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

open access: yesAdvanced Science, EarlyView.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen   +19 more
wiley   +1 more source

"Economic Development, Income Inequality and Social Stability in Prewar Japan: A Prefecture-level Analysis" [PDF]

open access: yes
This paper addresses the relationship between economic development, income inequality and social stability, using the data of prewar Japan. We have made prefecture-level income inequality index, based on tax and wage statistics with respect to four data ...
Tetsuji Okazaki
core  

The relative income hypothesis: does it exist over time? Evidence from the BHPS [PDF]

open access: yes, 2005
The relative income hypothesis suggests that income inequality has a detrimental affect on people´s health. This previously well accepted relationship has recently come under scrutiny.
Lindley, J., Lorgelly, P.
core  

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

open access: yesAdvanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen   +10 more
wiley   +1 more source

FAKTOR-FAKTOR YANG MEMPENGARUHI NILAI TUNGGAKAN KREDIT PADA PROGRAM PEMBERDAYAAN EKONOMI MASYARAKAT PESISIR DI KABUPATEN INDRAMAYU

open access: yesJurnal Ilmu Pertanian Indonesia, 2007
The objectives of this study were to analyze the income level of household, and to analyze the factors which influential non performance loan. This was a case study with purposive sampling method.
Alla Asmara
doaj  

Analyzing and comparing the impact of alternative concepts of resources in distributional studies: Greece, 2004/5 [PDF]

open access: yes
The usual practice in empirical distributional studies is to use either disposable income or consumption expenditure as a proxy for welfare. Essentially, both variables are used as approximations of the unobserved “permanent income” of the population ...
Panos Tsakloglou, Theodoros Mitrakos
core  

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