Results 91 to 100 of about 305,366 (295)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Evaluation of the Milionário bean cultivar as bridgecrossing between ‘Ruda’ and ‘Jalo EEP 558’

open access: yesCrop Breeding and Applied Biotechnology, 2004
This study evaluated the efficiency of the cultivar Milionário as bridge to incorporate alleles of resistance to angular leaf spot of the Andean cultivar Jalo EEP 558 into the Mesoamerican cultivar Rudd.
Lucianne Braga Oliveira Vilarinho   +3 more
doaj  

Effects of different pollination treatments in genotypes of Prunus salicina Lindl.

open access: yesInternational Journal of Horticultural Science, 2006
The low productivity in the Japanese plum (Prunus salicina Lindl) is related with self-incompatibility characteristics, so other species or varieties that act as pollinators need to be present to improve fruit production.
M. Ontivero   +3 more
doaj   +1 more source

Identifying the source of the problem by using implemented the FAHP method in the selected quality management techniques

open access: yesProduction Engineering Archives, 2020
Making a complex analysis of the problem in order to identify the root of its occurrence, is the process burdened with the risk of uncertainty. This risk is in case of the quality analysis, in which the choice and making a decision is not confirmed by ...
Siwiec Dominika, Pacana Andrzej
doaj   +1 more source

Strongly Incompatible Quantum Devices

open access: yes, 2013
The fact that there are quantum observables without a simultaneous measurement is one of the fundamental characteristics of quantum mechanics. In this work we expand the concept of joint measurability to all kinds of possible measurement devices, and we ...
Daniel Reitzner   +16 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Incompatibility, Product Attributes and Consumer Welfare: Evidence from ATMs [PDF]

open access: yes
Incompatibility in market with network effects reduces consumers? ability to ?mix and match? components offered by different sellers, but can also spur changes in product attributes that might beneÞt consumers.
Christopher Knittel, Victor Stango
core  

Incompatibility of unbiased qubit observables and Pauli channels

open access: yes, 2017
A quantum observable and a channel are considered compatible if they form parts of the same measurement device, otherwise they are incompatible. Constrains on compatibility between observables and channels can be quantified via relations highlighting the
Heinosaari, T.   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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