Stochastic Expectation Maximization Algorithm for Linear Mixed-Effects Model with Interactions in the Presence of Incomplete Data. [PDF]
Entropy (Basel), 2023 Zakkour A, Perret C, Slaoui Y.
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FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Updating mortality risk estimation in intensive care units from high-dimensional electronic health records with incomplete data. [PDF]
BMC Med Inform Decis Mak, 2023 Bouvarel B, Carrat F, Lapidus N.
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Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
X-ray data reconstruction from incomplete data sampling. [PDF]
J Appl CrystallogrMedina KG, Rams EE, Neder RB.
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Analytic continuation and incomplete data tomography. [PDF]
J Radiol Imaging, 2021 Zeng GL, Li Y.
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Corrigendum to "Handling errors in the response: Considerations for leveraging unsupervised or incomplete data for genetic evaluations" (JDS Commun. 5:675-680). [PDF]
JDS CommunWu XL +4 more
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Discussion on "Regression Models for Understanding COVID-19 Epidemic Dynamics with Incomplete Data". [PDF]
J Am Stat Assoc, 2021 Datta J, Mukherjee B.
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