Results 171 to 180 of about 45,544 (263)

Impact of incomplete lineage sorting and natural selection on the phylogenetic and taxonomic uncertainties of Aspidistra in Taiwan. [PDF]

Bot Stud
Luo MX, Yang MJ, Lu CT, Liao PC.
europepmc   +1 more source

Mitonuclear Discordance of Beetles Shaped by Incomplete Lineage Sorting and Introgression Under Loose Interaction Mechanism. [PDF]

Mol Biol Evol
Zhao T, Zhu P, Liu Q, Ma L, Xu Y, Lü L, Duan Y, Song F, Tian L, Cai W, Li H.   +10 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Ancient reticulation, incomplete lineage sorting and the evolution of the pyrenoid at the dawn of hornwort diversification. [PDF]

Ann Bot
Peñaloza-Bojacá G, Burleigh JG, Maciel-Silva A, Cargill DC, Bell D, Sessa EB, McDaniel SF, Davis EC, Endara L, Salazar Allen N, Li FW, Schafran P, Chantanaorrapint S, Duckett JG, Pressel S, Solís-Lemus C, Renzaglia KS, Villarreal A JC.   +17 more
europepmc   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Phylogenomic discordance is driven mainly by pervasive ancient hybridization and incomplete lineage sorting during the early divergence of major angiosperm lineages. [PDF]

Plant Commun
Huang X, Yang L, Ma X, Yang Z, Wang Q, Wang H, Yang Y, Morales-Briones DF, Zhong B.   +8 more
europepmc   +1 more source

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Joint Angular Excursions and Angular Range Utilization During Stance‐Phase Locomotion in Terrestrial Mammals: A Comparative Morphofunctional Data Set

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
This study quantifies stance‐phase joint angular excursions and angular utilization (AUI%) during walking in 182 terrestrial mammal species. Across mammals, total limb excursion during stance (TAE) decreases with increasing body mass, whereas AUI% remains broadly conserved, indicating similar proportional use of summed joint excursions to generate net ...
Paul Medina‐González
wiley   +1 more source

Extensive genome-wide phylogenetic discordance is due to incomplete lineage sorting in the rapidly radiated East Asian genus Nekemias (Vitaceae). [PDF]

Ann Bot
He GH, Meng Y, Zhang MH, Wang D, Meng R, Zhang L, Chu ZF, Wen J, Nie ZL.   +8 more
europepmc   +1 more source