Results 181 to 190 of about 44,475 (262)

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Joint Angular Excursions and Angular Range Utilization During Stance‐Phase Locomotion in Terrestrial Mammals: A Comparative Morphofunctional Data Set

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
This study quantifies stance‐phase joint angular excursions and angular utilization (AUI%) during walking in 182 terrestrial mammal species. Across mammals, total limb excursion during stance (TAE) decreases with increasing body mass, whereas AUI% remains broadly conserved, indicating similar proportional use of summed joint excursions to generate net ...
Paul Medina‐González
wiley   +1 more source

Mapping the Influence of Ansoff's Corporate Strategy

Strategic Change, EarlyView.
ABSTRACT This paper conducts a systematic, data‐driven analysis of H. Igor Ansoff's enduring impact on strategic management scholarship. Despite Ansoff's recognition as the “father of strategic management” and the continued relevance of his frameworks—including the Ansoff matrix, weak signals analysis, and strategic thrust—a comprehensive understanding
Ivan Zupic, Tomaž Čater, Andrea Caputo, Dejan Uršič   +3 more
wiley   +1 more source

Phytop: a tool for visualizing and recognizing signals of incomplete lineage sorting and hybridization using species trees output from ASTRAL. [PDF]

Hortic Res
Shang HY, Jia KH, Li NW, Zhou MJ, Yang H, Tian XL, Ma YP, Zhang RG.   +7 more
europepmc   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Phylogenomic Discordance is Driven by Wide-Spread Introgression and Incomplete Lineage Sorting During Rapid Species Diversification Within Rattlesnakes (Viperidae: Crotalus and Sistrurus). [PDF]

Syst Biol
Myers EA, Rautsaw RM, Borja M, Jones J, Grünwald CI, Holding ML, Grazziotin FG, Parkinson CL.   +7 more
europepmc   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Brownotate, a Comprehensive Solution to Generate Protein Sequence Databases for Any Species

PROTEOMICS, EarlyView.
ABSTRACT Proteomics is strengthening research in biology and the diversification of the model organisms studied is very promising for fully understanding the complexity of biological principles. However, the lack of protein sequence databases for many species is a major bottleneck.
Adrien Brown, Alexandre Burel, Sarah Cianférani, Christine Carapito, Fabrice Bertile   +4 more
wiley   +1 more source

An examination of introgression and incomplete lineage sorting among three closely related species of chocolate-dipped damselfish (genus: Chromis). [PDF]

Ecol Evol, 2019
He S, Robitzch V, Hobbs JA, Travers MJ, Lozano-Cortés D, Berumen ML, DiBattista JD.   +6 more
europepmc   +1 more source