Results 41 to 50 of about 807,608 (274)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra   +3 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Inconsistent Projections

open access: yesA Peer-Reviewed Journal About, 2022
In this paper we propose a time-based digital tool, a diagram-in-the-making, as to learn about computer vision in the field of security. With this method we want to map the heterogeneous and multiple nature of security vision tech- nologies and their imaginaries.
van de Ven , R., Plájás, I.Z.
openaire   +4 more sources

Noncommutativity Approach to Supersymmetry on the Lattice: SUSY Quantum Mechanics and an Inconsistency

open access: yes, 2006
It is argued that the noncommutativity approach to fully supersymmetric field theories on the lattice suffers from an inconsistency. Supersymmetric quantum mechanics is worked out in this formalism and the inconsistency is shown both in general and ...
Falk Bruckmann   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Inconsistency without Contradiction

open access: yesNotre Dame Journal of Formal Logic, 1997
My purpose in this paper is not to defend or attack the ersatz conception— the view that unactualized worlds are merely linguistic descriptions of the ways this world of ours might have been. Rather, I am interested in that conception insofar as it pertains to the challenge raised by Lewis.
openaire   +4 more sources

A dynamical inconsistency of Horava gravity

open access: yes, 2009
The dynamical consistency of the non-projectable version of Horava gravity is investigated by focusing on the asymptotically flat case. It is argued that for generic solutions of the constraint equations the lapse must vanish asymptotically.
Axel Kleinschmidt   +10 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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