Results 61 to 70 of about 815,427 (293)
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
This study proposes a novel state of health (SOH) estimation method by extracting two-level hierarchical features linked to fundamental degradation mechanisms.
Chaolong Zhang +7 more
doaj +1 more source
Inconsistency of interacting, multi-graviton theories
We investigate, in any spacetime dimension >=3, the problem of consistent couplings for a finite collection of massless, spin-2 fields described, in the free limit, by a sum of Pauli-Fierz actions.
Anco +55 more
core +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Accurate State-of-Health (SOH) estimation is a key technology for ensuring battery safety, optimizing energy management, and enhancing lifecycle value.
Yan Zhang +6 more
doaj +1 more source
Human (In)Consistencies in Ian McEwan’s Amsterdam
Ian McEwan’s Amsterdam has supplied its readers with psychological, moral and social topical issues presented in an easy flowing and exhilarating style. Starting from the assumption that life consists of a series of inconsistencies which are inherent and
Anghel Florentina
doaj +1 more source
The high rate of economic growth has encouraged the development of Baubau City in various sectors of life. It has implications on the increase in space requirements.
Fikril Fahmi +2 more
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source

