Cost-effectiveness analysis and incremental cost-effectiveness ratios
European Journal of Gastroenterology & Hepatology, 2004Cost-effectiveness analysis is a formal method of comparing alternative medical interventions with regard to their resource utilization (costs) and outcomes (effectiveness). The incremental cost-effectiveness ratio is an informative measure generated from such an analysis and represents the ratio of the difference in cost between two medical ...
Kiran, Bambha, W Ray, Kim
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Cost-effectiveness, QALYs, and incremental cost-effectiveness ratios
Seminars in Spine Surgery, 2014The cost of healthcare in the United States has continued to grow at an unsustainable rate. Spine care has not been immune to these elevating costs. Given the current economic environment, policy makers and payers have started to consider a move towards a system of value-based healthcare.
Ravi R. Patel +2 more
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Incremental cost-effectiveness ratios (ICERs): The silence of the lambda
Social Science & Medicine, 2006Despite the central role of the threshold incremental cost-effectiveness ratio (ICER), or lambda (lambda), in the methods and application of cost-effective analysis (CEA), little attention has been given to the determining the value of lambda. In this paper we consider 'what explains the silence of the lambda'?
Gafni, A, Birch, S
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Favorable incremental cost-effectiveness ratio for lung cancer screening in Italy
Lung Cancer, 2020Lung cancer detection by low-dose computed tomographic screening reduces mortality. However, it is essential to assess cost-effectiveness. We present a cost-effectiveness analysis of screening in Italians at high risk of lung cancer, from the point of view of the Italian tax-payer.We used a decision model to estimate the cost-effectiveness of annual ...
Giulia Veronesi +9 more
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A Study on Confidence Intervals for Incremental Cost‐Effectiveness Ratios
Biometrical Journal, 2008AbstractIn health policy and economics studies, the incremental cost‐effectiveness ratio (ICER) has long been used to compare the economic consequences relative to the health benefits of therapies. Due to the skewed distributions of the costs and ICERs, much research has been done on how to obtain confidence intervals of ICERs, using either parametric ...
Hongkun, Wang, Hongwei, Zhao
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Problems with Interval Estimates of the Incremental Cost—Effectiveness Ratio
Medical Decision Making, 1999The defining feature of a confidence interval is that it has a fixed minimum probability of covering the true value of the parameter being estimated, whatever the value of the parameter. The authors demonstrate by simulation that some recently proposed meth ods for interval estimation of the incremental cost—effectiveness ratio (ICER) either do not ...
D F, Heitjan, A J, Moskowitz, W, Whang
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UNCERTAINTY OF INCREMENTAL COST-EFFECTIVENESS RATIOS
International Journal of Technology Assessment in Health Care, 1999Objective: To compare different methods to estimate the confidence interval of the incremental cost-effectiveness ratio (ICER).Methods: The adequacy of Fieller intervals and three methods for calculating bootstrap intervals are compared based on a simulation of 10,000 trials, using data from one trial.Results: Both Fieller and bootstrap methods lead
Severens, J.L. +2 more
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Incremental and Average Cost‐Effectiveness Ratios: Will Physicians Make a Distinction?
Risk Analysis, 2003Physicians are increasingly asked to use cost‐effectiveness information when evaluating alternative health care interventions. Little is known about how the way such information is presented can influence medical decision making. We presented physicians with hypothetical screening scenarios with multiple options, varying the type of cost‐effectiveness ...
John C, Hershey +4 more
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On Estimating Medical Cost and Incremental Cost-Effectiveness Ratios with Censored Data
Biometrics, 2001Medical cost estimation is very important to health care organizations and health policy makers. We consider cost-effectiveness analysis for competing treatments in a staggered-entry, survival-analysis-based clinical trial. We propose a method for estimating mean medical cost over patients in such settings.
Zhao, Hongwei, Tian, Lili
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Incremental cost-effectiveness ratio and incremental net-health benefit: two sides of the same coin
Expert Review of Pharmacoeconomics & Outcomes Research, 2001In recent years, an alternative framework for cost-effectiveness analyses has been growing in popularity. Instead of the incremental cost-effectiveness ratio for which statistical inference is often difficult, the incremental net-health benefit (INHB), a linear transformation of incremental costs and effectiveness, has been utilized.
B A, Craig, M A, Black
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