Results 51 to 60 of about 1,529,381 (347)

Incremental Quantitative Analysis on Dynamic Costs

, 2016
In quantitative program analysis, values are assigned to execution traces to represent a quality measure. Such analyses cover important applications, e.g. resource usage. Examining all traces is well known to be intractable and therefore traditional algorithms reason over an over-approximated set.
Chu, Duc-Hiep, Jaffar, Joxan, Murali, Vijayaraghavan   +2 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A Proposed Fragility Curve Based on PO-ID Hybrid Analysis for Seismic Assessment Performance of the Reinforced Concrete Continuous Bridges in Earthquake Prone Area

Buildings
In earthquake-prone regions, the seismic performance assessment of reinforced concrete (RC) continuous bridges is critical for ensuring their resilience and safety.
Khin Thuzar Htay, Jafril Tanjung, Masrilayanti, Monita Olivia, Fadzli Mohamed Nazri, Mulyadi Bur   +5 more
doaj   +1 more source

Scalar and vector-valued fragility analysis of typical Algerian RC bridge piers

Građevinar, 2023
This paper presents and discusses an approach for performing scalar and vector vulnerability assessments of typical Algerian RC bridge piers. Across incremental dynamic analysis, the seismic response was calculated while considering 60 seismic ground ...
Fouad Kehila, Mebarek Khelfi, Mounir Ait Belkacem   +2 more
doaj   +1 more source

Numerical Simulation of Unreinforced Masonry Buildings with Timber Diaphragms

Buildings, 2021
Though flexible diaphragms play a role in the seismic behaviour of unreinforced masonry buildings, the effect of the connections between floors and walls is rarely discussed or explicitly modelled when simulating the response of such buildings.
Igor Tomić, Francesco Vanin, Ivana Božulić, Katrin Beyer   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Assessing Material Fragility using Nanoscale Incremental Dynamic Analysis [PDF]

, 2021
A new methodology to assess material failure subjected to stochastic loads is proposed, titled Nanoscale Incremental Dynamic Analysis (NIDA), which is adopted from performance-based assessment in structural engineering. Using full atomistic molecular dynamics, proof-of-concept simulations produce the material fragility curve of a simple carbon nanotube.
openaire   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

opseestools: A Python library to streamline OpenSeesPy workflows

SoftwareX
OpenSees, a framework for nonlinear structural analysis, has significantly advanced seismic research and practice. The introduction of OpenSeesPy in 2018, which integrated Python as an interpreter alongside TCL, greatly enhanced the framework's utility ...
Orlando Arroyo, Dirsa Feliciano, Daniela Novoa, Jairo Valcárcel   +3 more
doaj   +1 more source

Seismic Repair Cost-Based Assessment for Low-Rise Reinforced Concrete Archetype Buildings through Incremental Dynamic Analysis

Buildings, 2023
This study presents the performance-based seismic assessment of low-rise reinforced concrete archetype buildings, considering repair costs for ordinary moment-resistant frames (OMF) and dual systems consisting of OMF plus special shear walls (SSW ...
Juan Patricio Chicaiza-Fuentes, Ana Gabriela Haro-Baez   +1 more
doaj   +1 more source