Results 221 to 230 of about 440,724 (260)

From Perception to Reality: Overcoming Toxicity Barriers in Healthcare Material Innovation

Advanced Therapeutics, EarlyView.
Materials innovation is transforming healthcare but faces regulatory and toxicity‐related barriers, particularly in nanotechnology and inorganic systems. Strategies are outlined to bridge innovation and regulation through early toxicological screening, interdisciplinary co‐design, computational modeling, life cycle analysis, and post‐market ...
Inge K. Herrmann, Peter Wick
wiley   +1 more source

Safe Reinforcement Learning in Flight Control: Introduction to Safe Incremental Dual Heuristic Programming

, 2020
Rick Feith
openalex   +1 more source

Regular versus Irregular Exercise Differentially Modulates Hippocampal‐Hepatic Acetylcholine Flux to Coordinate Fear Memory Extinction and Liver Inflammation

Advanced Science, EarlyView.
Ma et al. report the hippocampal and hepatic acetylcholine (ACh) levels are differently modulated by regular versus irregular exercise, which contributes to coordinate hippocampal astrocyte activity and hepatic FBXL6high neutrophil recruitment. This ACh‐modulated brain‐liver circuit links the effects of exercise on fear memory extinction and liver ...
Pengjiao Ma, Kuan Zhang, Long Yi, Chuanyan Yang, Hedong Lang, Jianbin Sun, Jin Li, Qian Bai, Yuhang He, Shuang‐Shuang Dai, Man‐Tian Mi   +10 more
wiley   +1 more source

Adaptive recognition of machining features in sheet metal parts based on a graph class-incremental learning strategy. [PDF]

Sci Rep
Ma L, Yang J.
europepmc   +1 more source

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

Advanced Science, EarlyView.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi, Qi‐Long Tang, Jin‐Hong Wang, Yan‐Lan Long, Sai‐Feng Zhao, Zhen Zhao, Wan‐Ting Xie, Zi‐Ming Li, Hao‐Ming Lu, Tian‐Xiao Gao, Zhen‐Zhen Fang, Ti Zhou, Bo‐Xing Li, Xia Yang, Guo‐Quan Gao, Wei‐Wei Qi   +15 more
wiley   +1 more source

Semi-supervised class incremental learning for computer vision

, 2021
Alexis Lechat
openalex   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

GBDT-IL: Incremental Learning of Gradient Boosting Decision Trees to Detect Botnets in Internet of Things. [PDF]

Sensors (Basel)
Chen R, Dai T, Zhang Y, Zhu Y, Liu X, Zhao E.   +5 more
europepmc   +1 more source

A Comparative Analysis of Liquid Neural Networks and Incremental Learning Approaches for Stock Market Prediction

Hussein Jammal, Farah Srour, Salman Ali, Michel Owayjan, Omran Ayoub, Cristina Rottondi, Roger Achkar   +6 more
openalex   +2 more sources

REAL: Representation Enhanced Analytic Learning for Exemplar-free Class-incremental Learning [PDF]

Run He, Huiping Zhuang, Di Fang, Yizhu Chen, Kai Tong, Cen Chen   +5 more
openalex   +1 more source