Results 111 to 120 of about 281,431 (254)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Composition and Functional Properties of Tender Coconut Water: Effect of Variety and Maturity Stage

Future Postharvest and Food
This study investigated the effects of three coconut varieties—Malayan Yellow Dwarf (MYD), Malayan Orange Dwarf (MOD), and Chowghat Orange Dwarf (COD)—harvested at 6‐, 7‐, and 8‐month maturity on the physicochemical, nutritional, enzymatic, and sensory ...
Raja Vijayakumar, Suruthi Muthusamy, Shubham Nimbkar, Thirukumaran Ramesh, Aditi Negi, Jeyan Arthur Moses, Vadakkepulppara Ramachandran Nair Sinija   +6 more
doaj   +1 more source

Suppression of phytopathogenic fungi using garlic, horsetail, and yarrow plant extracts [PDF]

Journal of Central European Agriculture
Organic production is a system of sustainable agriculture based on a high respect for environmental principles through the rational use of natural resources, renewable energy sources, conservation of natural diversity, and environmental protection. Plant
Saud Hamidović, Berina IMAMOVIĆ, Fejzo BAŠIĆ, Muamer BEZDROB, Nermin RAKITA, Blažo LALEVIĆ   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Eggs in the freezer: energetic consequences of nest site and nest design in Arctic breeding shorebirds [PDF]

, 2012
Birds construct nests for several reasons. For species that breed in the Arctic, the insulative properties of nests are very important. Incubation is costly there and due to an increasing surface to volume ratio, more so in smaller species. Small species
Hans Schekkerman, Tulp Ingrid, Leeuw, J.J., de, Ingrid Tulp, de Leeuw, J.J., Joep de Leeuw, Tulp, I., Schekkerman, H., Tulp, I.Y.M., de Leeuw Joep, Schekkerman Hans, Tulp, Ingrid, Sveriges lantbruksuniversitet., De Leeuw, Joep, De Leeuw, Joep,, Hans, Schekkerman   +15 more
core   +2 more sources

New horizons of microphysiological systems: India forging its path in human-relevant research

Biology Open, 2023
Surat Parvatam, Kasturi Mahadik, Anushka Banerjee, Kadambari Patil, V. Radha, Madhusudhana Rao   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

New business ideas incubation process: some exploratory findings of three Portuguese business incubation programs

The ever increasing competition in which firms operate at a global scale and the need to shift the type of economic growth have led countries to adopt instruments that give them a competitive advantage and deliver growth based on entrepreneurship and
Polónia, Daniel, Leite, Tiago, Cunha, Jorge, Tiago Resende Leite, Jorge Cunha, Daniel Ferreira Polónia   +5 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The energetic costs of incubation

, 2015
This chapter discusses several different aspects of the energy balance and physiological homeostasis of incubating birds, ranging from systematic, geographical and life history related variation in energy costs of incubation, to thermal considerations ...
Nord, Andreas,, Lund University., Williams, Joseph B.   +2 more
core