Results 241 to 250 of about 1,673,307 (292)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

The influence of salivary contamination during light curing on degree of conversion and color stability of two composite resins. [PDF]

J Oral Biol Craniofac Res
Rohaninasab M, Falahat S, Tayebi G, Manouchehri F, Mahounak FS.   +4 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Toward same-day detection of <i>Salmonella</i>: a rapid and cost-effective analytical method. [PDF]

Front Microbiol
Cristiano D, Peruzy MF, Castellano S, Mancusi A, Proroga YTR, Delibato E, Mazzocca R, Ambrosio RL, Murru N.   +8 more
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Association of serotonin and ergot alkaloids on tissue partitioning and contractile response of bovine blood vessels. [PDF]

Curr Res Toxicol
Valente EEL, Harmon DL, May J, Ji H, Trotta RJ, Klotz JL.   +5 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Enzyme-Mediated Precipitation of Heavy Metals Using Urease Extracted from <i>Sporosarcina pasteurii</i>. [PDF]

Iran J Biotechnol
Joukar A, Mohammadi M, Ghezelbash GR.
europepmc   +1 more source

Early Developmental Decline in HSP Expression Affects Subsequent Response to Transient Heat Exposure. [PDF]

Integr Org Biol
Warren CR, Wilken MB, Rollins JM, Paitz RT, Bowden RM.   +4 more
europepmc   +1 more source