Results 51 to 60 of about 1,204,472 (329)

Transient and permanent effects of suboptimal incubation temperatures on growth, metabolic rate, immune function and adrenocortical responses in zebra finches [PDF]

, 2015
n birds, incubation temperature can vary by several degrees Celsius among nests of a given species. Parents may alter incubation temperature to cope with environmental conditions and/or to manipulate embryonic development, and such changes in incubation ...
Allen, Natalie, Kriengwatana, Buddhamas, MacDougall-Shackleton, Scott A., Schmidt, Kimberly L., Soma, Kiran K., Wada, Haruka   +5 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]

, 2008
The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Andréoletti, Angela Chong, Bishop, Brown, Castilla, Clarke, Fiona Houston, Goldmann, Goldmann, Goldmann, González, González, Gregori, Gregori, Hadlow, Hewitt, Hill, Hilton, Houston, Houston, Hunter, Ironside, James Foster, Jeffrey, Jeffrey, Jeffrey, Kirby, Llewelyn, Lorenzo González, Martin Jeffrey, Mead, Nora Hunter, O'Rourke, Peden, Sandra McCutcheon, Saá, Schreuder, Silvia Sisó, Sisó, Valleron, van Keulen, Wilfred Goldmann, Will, Wroe   +43 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Integrated nutrient management to enhance biochemical resistance in rice against sheath blight [PDF]

, 2009
Application of potassium either as recommended, deficient or excess dose, enhanced the level of phenolic contents, increased incubation period and thereby decreased the sheath blight severity.
Prasad, Durga, Singh, Alka, Singh, Ramji
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Characterizing COVID-19 Transmission: Incubation Period, Reproduction Rate, and Multiple-Generation Spreading

Frontiers in Physics, 2021
Understanding the transmission process is crucial for the prevention and mitigation of COVID-19 spread. This paper contributes to the COVID-19 knowledge by analyzing the incubation period, the transmission rate from close contact to infection, and the ...
Lin Zhang, Jiahua Zhu, Xuyuan Wang, Juan Yang, Xiao Fan Liu, Xiao-Ke Xu   +5 more
doaj   +1 more source

A Method for the Rapid Cultivation of Desulfovibrio aestuarii on Filter Membranes [PDF]

, 1958
The cultivation of sulfate-reducing bacteria on agar plates is a somewhat involved and time-consuming process. This is partly due to the requirement for fairly strict anaerobic conditions but mainly because of the length of the incubation period which ...
Goetz, A., Tsuneishi, N.
core   +1 more source

The minimal incubation period from the onset of Barrett's oesophagus to symptomatic adenocarcinoma [PDF]

, 2011
Background:The interval between the onset of Barrett's oesophagus (BO) and oesophageal adenocarcinoma (OAC) can be termed the incubation period. However, the unrecorded onset of BO precludes its direct observation.Methods:Determining the range of ...
Blankenstein, M. (Mark) van, Dees, J. (Jan), Hoed, C.M. (Caroline) den, Kuipers, E.J. (Ernst)   +3 more
core   +3 more sources