Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Key Factors Affecting a Technology Entrepreneur's Choice of Incubator or Accelerator [PDF]
Technology entrepreneurship rarely succeeds in isolation; increasingly, it occurs in interconnected networks of business partners and other organizations.
Diane A. Isabelle
doaj
An incubator model based on the territorial value chain
Policies to promote and encourage local foods may take many different shapes depending on both the specific targets and strategies. Some policies, especially at a local level, promote supply-chain vertical and horizontal integration as a comprehensive ...
Francesco Contò +3 more
doaj +1 more source
E-catalogue Inkubator Bisnis Ibi Darmajaya [PDF]
IBI Darmajaya is one of the universities in Lampung, which has the vision of becoming a college superior and competitive base in technology and business.
Lestari, S. (Sri) +2 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Incubator Age and Incubation Time: Determinants of Firm Survival after Graduation? [PDF]
On the basis of a sample of 149 graduate firms from five German technology oriented business incubators, this article contributes to incubator/incubation literature by investigating the effects of the age of the business incubators and the firms ...
Michael Schwartz
core
Analisis Pendapatan USAhatani Semangka di Inkubator Agribinis (Studi Kasus Petani Semangka Binaan Inkubator Agribisnis Universitas Riau) [PDF]
Incubator of agribusiness is one of watermelon production center in Pekanbaru City. The land on Agribusiness Incubator is very suitable to grow watermelon, it is possible if planted watermelon produced will be good and quality.
Eliza, E. (Eliza) +2 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Exploring the Barriers to the Development of Agricultural Businesses in technology Incubators: A case Study of razi university Incubator, Iran [PDF]
The main objective of the present study was to explore the barriers to the development of agricultural businesses in the incubator of Razi University, Iran.
Bijan Rezaee +2 more
doaj
Determining organisms’ responses to novel temperatures is relevant from ecological, evolutionary, and conservation perspectives. Here, we have validated designs and included biological examples for three affordable devices to estimate thermal responses ...
Carlos Garcia‐Robledo +4 more
doaj +1 more source

