Results 81 to 90 of about 689,327 (304)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Applied SciencesGas plays a crucial role in cell culture as cells require a specific gas environment to maintain their growth, reproduction, and function. Here, we propose a gas supply system for tri-gas multi-channel cell incubators to meet the specific needs of ...
Donggen Xiao +4 more
doaj +1 more source
Sensors, 2014 Precise temperature measurement is essential in a wide range of applications in the medical environment, however the regarding the problem of temperature measurement inside a simple incubator, neither a simple nor a low cost solution have been proposed ...
Robert Frischer +4 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Is Joining a Business Incubator or Accelerator Always a Good Thing?
Technology Innovation Management Review, 2019 Business incubators and accelerators are often hailed as essential tools for fostering growth in startups. However, not only do entrepreneurs often face the question of which incubator or accelerator to join, we suggest that they should also question ...
Kristina Lukosiute +2 more
doaj +1 more source
Supporting SME start-up in Slovakia by means of business incubators [PDF]
Business incubators began in the 1960s and really took off in the late 1990s as support for start up companies who need advice and venture capital to get their ideas off the ground.
György Kadocsa, ¼ubica Lesáková
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Sri Lanka Social Enterprise Needs Assessment and Advisory [PDF]
, 2014 Authored in collaboration with Oxfam, this research maps social enterprises within the agriculture sector, identifies the key challenges they face, and makes recommendations for donors and development agencies looking to support the space in Sri Lanka ...
Alison Eskesen, Rashi Agrawal
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Administrative SciencesDespite the growing role of business incubators in fostering digital startups in emerging economies, the mechanism through which business incubator characteristics, specifically relational capital and structural embeddedness, influence startup innovation
Adhi Bawono +3 more
doaj +1 more source
Backpropagation Artificial Neural Network To Detect Hyperthermic Seizures In Rats [PDF]
, 2002 A three-layered feed-forward back-propagation Artificial Neural Network was used to classify the seizure episodes in rats. Seizure patterns were induced by subjecting anesthetized rats to a Biological Oxygen Demand incubator at 45-47ºC for 30 to 60 ...
Sinha, Mr Rakesh Kumar
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