Results 91 to 100 of about 689,327 (304)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Understanding and Design of an Arduino-based PID Controller [PDF]
, 2016 This thesis presents research and design of a Proportional, Integral, and Derivative (PID) controller that uses a microcontroller (Arduino) platform. The research part discusses the structure of a PID algorithm with some motivating work already performed
Bista, Dinesh
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
European Journal of Translational MyologyThis is a personal account of one academic scientist who founded two biotechnology companies. Both companies were initially incubated within the walls of the university under a creative student incubator program whereby biology students could pursue ...
Roger Sabbadini
doaj +1 more source
Applied Sciences, 2019 Mathematical models of body heat exchanges can be used to define the thermal limits needed to protect premature neonates nursed in incubators against thermal stress–stress that can have potentially devastating impairments on neurological ...
Stéphane Delanaud +4 more
doaj +1 more source
Business Incubation Developmentin India [PDF]
The paper provides the experience of setting up first incubator for grassroots innovations in the form of GIAN (Grassroots Innovation Augmentation Network) and make a case for replicating this model elsewhere in the developing world.
Gupta, Anil K.
core
Performance differentials of agglomeration and strategic groups: a test of incubation and new venture strategy [PDF]
, 2013 Our paper investigates how nascent firms ‘performance is affected by strategic group membership and industrial agglomeration. Agglomeration is defined using geographical concentration while strategic groups are measured as incubated firms that belong to ...
Amezcua, A.S. +2 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
An incubator model based on the territorial value chain
Apstract: Applied Studies in Agribusiness and Commerce, 2013 Policies to promote and encourage local foods may take many different shapes depending on both the specific targets and strategies. Some policies, especially at a local level, promote supply-chain vertical and horizontal integration as a comprehensive ...
Francesco Contò +3 more
doaj +1 more source