Results 51 to 60 of about 436,071 (266)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Key Factors Affecting a Technology Entrepreneur's Choice of Incubator or Accelerator [PDF]

open access: yesTechnology Innovation Management Review, 2013
Technology entrepreneurship rarely succeeds in isolation; increasingly, it occurs in interconnected networks of business partners and other organizations.
Diane A. Isabelle
doaj  

Reconciling Resource-Based View and Competency-Based View of Start-Up Formation in Universities

open access: yesIEEE Access, 2020
Given the industrial and economic importance of start-up formation in universities, researchers have adopted a variety of theoretical approaches, including embeddedness theory, ecosystem theory, resource-based view (RBV), and competency-based view (CBV).
Kyoung-Joo Lee, Yang-Joong Yun
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The Eco-System, Barriers and Factors of Sustainable Growth Social Economy in Armenia

open access: yesBanber Erevani Hamalsarani. Sots'iologia, 2020
Thanks to the international donor community, in recent years, the concept of social entrepreneurship has become a factor in the regulation of socio-economic and local problems in Armenia.
Anna Malkhasyan
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Exploring the Barriers to the Development of Agricultural Businesses in technology Incubators: A case Study of razi university Incubator, Iran [PDF]

open access: yesInternational Journal of Agricultural Management and Development, 2018
The main objective of the present study was to explore the barriers to the development of agricultural businesses in the incubator of Razi University, Iran.
Bijan Rezaee   +2 more
doaj  

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