Results 51 to 60 of about 478,181 (301)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Business, Management and Economics EngineeringPurpose – This study focuses on the evaluation of youth platforms as an important social incubator of the National Initiative for Human Development (NIHD) in Morocco, particularly to promote social entrepreneurship and support very small enterprises ...
Younes El Maaqili +2 more
doaj +1 more source
Exploring the feasibility of applying a conceptual model of soft systems methodology in implementing a management information system in Universities of Medical Sciences incubators [PDF]
Journal of Health Management & Informatics, 2020 Introduction: A management information system (MIS) can have a great effect on the effectiveness and efficiency of management in different centers. Various conceptual models are used for designing, implementing, and evaluating this system.
Nahal Aarabi +3 more
doaj
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Practicality and Effectiveness of New Technopreneurship Incubator Model in The Digitalization Era
Aptisi Transactions on TechnopreneurshipThe development of business incubators within colleges is gaining traction in Indonesia as a strategic approach to fostering business start-up innovation and enhancing entrepreneurial interest among younger generations.
Larisang Larisang +3 more
doaj +1 more source
Incubators for innovators [PDF]
Nature Biotechnology, 2015 There are many points to consider when deciding whether to locate your business in an incubator.
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Frontiers in Immunology, 2022 The COVID-19 pandemic has had a devastating impact worldwide and has been a great challenge for the scientific community. Vaccines against SARS-CoV-2 are now efficiently lessening COVID-19 mortality, although finding a cure for this infection is still a ...
Chiara Ripamonti +12 more
doaj +1 more source