Results 141 to 150 of about 3,053 (246)

Blocking SETD2 Enhances the Therapeutic Efficiency of Menin Inhibitor in MLL‐Fusion Leukemia

Cancer Science, EarlyView.
Combined SETD2 and menin inhibitors make synergistic effects against MLL‐fusion leukemia; the combination therapy reduces the expression of target genes through blocking transcription elongation and initiation. ABSTRACT During transcriptional elongation, the histone methyltransferase SETD2 binds to RNA polymerase II and deposits trimethylation marks at
Anpei Li, Yuan Zhang, Ziwei Li, Anhao Liu, Li Zhang, Shubin Gao, Xiao Lin, Xiaoming Liu, Huan Li, Guanghui Jin, Bin Xu   +10 more
wiley   +1 more source

Supporting Parental Decision-Making After Life-Limiting Fetal Diagnoses: The Role of Perinatal Hospice and the NOVA-L Decision Support System. [PDF]

Healthcare (Basel)
Dahò M.
europepmc   +1 more source

Transient Hyperparathyroidism and Severe Intrauterine Osteopenia Linked to Novel Homozygous TRPV6 Deletion

Clinical Endocrinology, EarlyView.
ABSTRACT Context Placental calcium (Ca2+) transport is essential for foetal bone mineralisation and development, as well as for Ca2+ homoeostasis. Rare mutations in transient receptor potential vanilloid (TRPV) 6 of the infant cause insufficient maternal‐foetal Ca2+ transport through the placenta.
Teodora Grigore, Quinty Leusink, Femke Latta, Bram van der Eerden, Paul de Laat, Danielle van der Kaay, Joost Hoenderop   +6 more
wiley   +1 more source

Surrogate skin-to-skin care: the "donor milk" of kangaroo mother care. [PDF]

J Perinatol
Nitzan I, Phillips R, White RD, Rüdiger M, Rogers EE.   +4 more
europepmc   +1 more source

Exploring How Affordances of Play Materials Shape Chinese Parents' Interaction With Children: Media‐Elicited Focus Group Discussion

Children &Society, EarlyView.
ABSTRACT Existing literature on children's play materials predominantly reflects theoretical frameworks and empirical data generated in the Global North, where ideas of “developmental appropriateness” often overlook the socio‐cultural specificity of materials' affordances and parental expectations.
Zhiyu Zhang, Jingyun Zhang
wiley   +1 more source

Effects of hydrotherapy and hammock positioning on pain reduction in preterm neonates. [PDF]

J Pediatr (Rio J)
da Silva ATVAR, Arcanjo FPN, Justino JS, Teles LA, de Aquino AKM.   +4 more
europepmc   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

Cell Proliferation, EarlyView.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang, Qizhi Wang, Yu Wu, Chen Gu, Mingfei Li, Yong Fan, Xiangjin Kang, Lei Li, Zheng Gao, Mingyan Hei, Jianqiao Liu, Lei Li   +11 more
wiley   +1 more source

Humming and Homeostasis: Insights from Infants, Mothers, Mantras and Caregiving. [PDF]

Behav Sci (Basel)
Gratier M, Carvalho ME.
europepmc   +1 more source

Biocultural Approaches in the Society for the Anthropology of Food and Nutrition: A Reflection on 50 Years

Culture, Agriculture, Food and Environment, EarlyView.
ABSTRACT On the occasion of SAFN's 50th anniversary I reflect on the development of biocultural and human evolutionary approaches to human diet and nutrition. I maintain that SAFN and its predecessors the Committee (1974–1987) and then Council on Nutritional Anthropology (1987–2004) have modeled, fostered, and advanced biocultural work in anthropology ...
Andrea S. Wiley
wiley   +1 more source

Reflections on a global partnership for perinatal quality improvement in Rwanda. [PDF]

BMJ Paediatr Open
Tuyisenge L, Habonimana JP, Nsengiyumva A, Cyiza FR, Manzi E, Desie S, Pledge A, McMurtrie S, Muzard-Banes C, Bontoux M, Taylor S.   +10 more
europepmc   +1 more source