Results 31 to 40 of about 25,605 (265)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Design thinking as a medium of professionalism and learning: A case of business incubator

open access: yesCogent Arts & Humanities, 2018
This article is a case study that explores the understanding of design thinking strategies undertaken by final year students in the field of design and architecture in Business Incubator (BI) projects.
Filipus Priyo Suprobo
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Parametric Audio Based Decoder and Music Synthesizer for Mobile Applications

open access: yesArchives of Acoustics, 2013
This paper reviews parametric audio coders and discusses novel technologies introduced in a low-complexity, low-power consumption audio decoder and music synthesizer platform developed by the authors. The decoder uses parametric coding scheme based on
Marek SZCZERBA   +2 more
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A Framework of Successful Business Incubators for Indonesian Public Universities

open access: yesInternational Journal of Technology, 2016
Universities play an important role in motivating young graduates to become technology entrepreneurs. The objectives of this research are to investigate the success factors for business incubators and to develop and propose a framework of successful ...
Lina Gozali   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

INCUBADORAS TECNÓLOGICAS DE COOPERATIVAS POPULARES: ATUANDO A PARTIR DA EXTENSÃO UNIVERSITÁRIA

open access: yesRevista Gestão Universitária na América Latina, 2016
This work is a result of research on the mapping of techno - social Incubators Cooperatives (ITCP) held in southern Brazil, which aims to analyze the current situation of these. The methodology used for this research was
Louise de Lira Roedel Botelho   +5 more
doaj  

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