Results 31 to 40 of about 1,930 (114)

Hematopoietic effects of tagraxofusp in treatment‐naive patients with blastic plasmacytoid dendritic cell neoplasm

Cancer, Volume 132, Issue 1, 1 January 2026.
Abstract Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN), an aggressive hematologic neoplasm that expresses CD123, is often observed in the bone marrow (BM), as well as skin, blood, and viscera. Tagraxofusp, a first‐in‐class CD123‐targeted therapy, is the only drug approved to treat BPDCN.
Marina Konopleva, Naveen Pemmaraju, Kendra L. Sweet, Anthony S. Stein, David A. Rizzieri, Eunice S. Wang, Sumithira Vasu, Todd Rosenblat, Michael Zuurman, Ira Gupta, Andrew A. Lane   +10 more
wiley   +1 more source

As políticas de inovação para a indústria farmacêutica da Índia entre 2005 e 2019:

Textos de Economia, 2023
Este artigo analisa as políticas de inovação para a indústria farmacêutica indiana entre 2005 e 2019. Por meio de revisão de literatura e análise documental das políticas que mais incidem sobre a capacidade produtiva e tecnológica dessa indústria ...
Daniela Falcão, Julia Paranhos
doaj   +1 more source

Quality Infrastructure for Resilient Pharmaceutical Manufacturing in Ethiopia: A Comparative Archival Review

Journal of Critical Infrastructure Policy, Volume 7, Issue 1, Spring/Summer 2026.
ABSTRACT The National Quality Infrastructure (NQI) in a given country provides the essential framework for quality assurance integrating standardization, metrology, accreditation, and conformity assessment to create the technical backbone for industry and trade. Hence, building a resilient NQI is fundamental to securing medicine quality, enabling local
Addisu Afrassa Tegegne, Mesfin Demissie Woldecherkos, Habtewold Deti Waktola, Sultan Suleman   +3 more
wiley   +1 more source

A publicidade de alimentos e o direito à saúde

Revista de Direito Sanitário, 2007
Este trabalho analisa a monitoração e fiscalização da propaganda de produtos sujeitos à vigilância sanitária, um processo influenciado por mudanças sociais e econômicas, pela evolução da ciência e pelo ordenamento jurídico.
Maria José Delgado Fagundes, Rodrigo Fagundes Souza   +1 more
doaj  

A Novel In Vitro Host−Pathogen Model for Felis catus and Sporothrix Zoonotic Species Investigation

Journal of Basic Microbiology, Volume 65, Issue 10, October 2025.
ABSTRACT Hyperendemic zoonotic sporotrichosis, attributed to Sporothrix brasiliensis, presents a significant public health challenge in Brazil. Cats exhibit severe symptoms and high fungal loads, though their susceptibility is unclear. Sporothrix schenckii can also cause feline disease, primarily seen in Asia.
Gabriele Barros Mothé, Nathália Faria Reis, Emylli Dias Virginio, Miguel Angelo da Silva Medeiros, Adriany Lucas dos Santos, Júlia Andrade de Castro Rodrigues, Ricardo Luiz Dantas Machado, Gutemberg Gomes Alves, Nathália Curty de Andrade, Leila Maria Lopes‐Bezerra, Andréa Regina de Souza Baptista   +10 more
wiley   +1 more source

Canagliflozin reduces oral loop diuretic intensification in patients with type 2 diabetes: A participant‐level pooled analysis of the CANVAS and CREDENCE trials

European Journal of Heart Failure, Volume 27, Issue 6, Page 994-1002, June 2025.
Among high‐risk patients with type 2 diabetes, new oral loop diuretic intensification was frequent and portended adverse prognostic significance. Treatment with canagliflozin significantly reduced the need for loop diuretic intensification. CI, confidence interval; CKD, chronic kidney disease; CV, cardiovascular; HF, heart failure; HR, hazard ratio ...
Safia Chatur, Muthiah Vaduganathan, Robert A. Fletcher, Vlado Perkovic, Hiddo Heerspink, Clare Arnott, Carol Pollock, Kenneth W. Mahaffey, Bruce Neal, Meg Jardine, Scott D. Solomon, Brendon L. Neuen   +11 more
wiley   +1 more source

Treatment and outcome of gall bladder leiomyoma in an asymptomatic dog

Veterinary Record Case Reports, Volume 13, Issue 2, June 2025.
Abstract The purpose of this report was to describe the diagnostic protocol, treatment and outcome of an 11‐year‐old, entire male, mixed‐breed dog with a gall bladder neoplasia histologically consistent with a leiomyoma. On referral, the patient had no clinical signs related to the gall bladder mass.
Elisa Pizzi, Stefano Zanardi, Andrea Renzi, Ilaria Maga, Sara Del Magno   +4 more
wiley   +1 more source

Expert opinion on gray areas in asthma management: A lesson from the innovative project “revolution in asthma” of the Italian thoracic society (AIPO‐ITS)

Clinical and Translational Allergy, Volume 15, Issue 2, February 2025.
Abstract Background Despite the availability of numerous guidelines for asthma management, their recommendations are not consistently implemented in clinical practice. This discrepancy between guidelines and real‐world practice among Italian healthcare professionals was explored during the “Revolution in Asthma” training program, which identified “gray
Adriano Vaghi, Raffaele Antonelli Incalzi, Simona Barbaglia, Maria Beatrice Bilò, Francesco Bini, Mauro Carone, Lorenzo Cecchi, Alfredo Antonio Chetta, Andrea Claudio Comel, Fausto De Michele, Giuseppe Insalaco, Antonino Musarra, Giovanni Pomponio, Antonio Spanevello, Silvia Tognella, Alessandro Vatrella, Lina Zuccatosta, Claudio Micheletto   +17 more
wiley   +1 more source

Saúde, medicamentos, marketing e médicos

Revista Portuguesa de Medicina Geral e Familiar, 2008
O presente artigo introduz uma visão muito sintética da situação da Saúde em Portugal e do seu posicionamento em relação a outros países com um grau de desenvolvimento semelhante.
Luís Dos Santos Ferreira
doaj   +1 more source

Drug Discovery Approaches to Target E3 Ligases

ChemBioChem, Volume 26, Issue 1, January 2, 2025.
Comprehensive review presenting the different drug discovery approaches that until now have been employed in academic and pharmaceutical settings to identify new E3 ligase small molecules ligands and contributing to the expansion of the targeted protein degradation field. Abstract Targeting E3 ligases is a challenging area in drug discovery.
Alejandra Rodríguez‐Gimeno, Carles Galdeano   +1 more
wiley   +1 more source