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Pharmacokinetics and clinical pharmacology of indapamide
American Heart Journal, 1983Indapamide is a new antihypertensive diuretic agent indicated for the treatment of hypertension and edema. Indapamide shows an alteration in vascular reactivity to calcium and other agonists, suggesting the possibility of a direct vascular effect. The drug is recommended in doses of 2.5 to 5 mg once a day. It is rapidly and completely absorbed from the
Frank S Caruso +2 more
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Long-term experience with indapamide
American Heart Journal, 1983Indapamide, 2.5 mg administered once daily for periods up to 36 months, was found to be safe and effective for the long-term control of mild to moderate hypertension. The effects of hydrochlorothiazide, 50 mg, and indapamide, 2.5 mg, were studied in two randomized, double-blind, multicenter trials.
Robert A Vukovich +5 more
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Cardiovascular Protective Properties of Indapamide
The American Journal of Cardiology, 1990Although indapamide has been used for many years as a first-line treatment of hypertension, it is only recently that some of its activities on the changes of the cardiovascular system, brought on by age and high blood pressure, have been studied. Indapamide appears to reduce blood pressure by a combined diuretic and direct vascular activity reducing ...
Campbell Db, Brackman F
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Photo‐onycholysis due to indapamide
Australasian Journal of Dermatology, 2007SUMMARYPhoto‐onycholysis due to indapamide presented in a 75‐year‐old woman who was being treated with the diuretic for hypertension. The onset of her photo‐onycholysis was delayed because of inadvertent photoprotection in the form of artificial nails and occurred in the absence of a generalized photosensitive eruption.
Rodney Sinclair, Tim Rutherford
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Indapamide: A Unique Diuretic?
Drug Intelligence & Clinical Pharmacy, 1983Indapamide (Lozol) is a new diuretic and antihypertensive agent. The drug appears to have a unique mechanism of action, combining diuretic effects with a direct vascular action, presumably secondary to calcium channel blockade. Available studies indicate that Indapamide is comparable to hydrochlorothiazide, chlorothiazide, furosemide, and other ...
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Analytica Chimica Acta, 2005
Abstract A chemiluminescence reaction between soluble Mn(IV) and indapamide was found. An indapamide MIP was synthesized and its adsorption selectivity to indapamide in aqueous solution was evaluated. Using soluble Mn(IV)–formaldehyde–indapamide chemiluminesence system as detection system and the indapamide MIP as recognition material, a selective ...
Nie Fei, Niu Weifen, Lu Jiuru
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Abstract A chemiluminescence reaction between soluble Mn(IV) and indapamide was found. An indapamide MIP was synthesized and its adsorption selectivity to indapamide in aqueous solution was evaluated. Using soluble Mn(IV)–formaldehyde–indapamide chemiluminesence system as detection system and the indapamide MIP as recognition material, a selective ...
Nie Fei, Niu Weifen, Lu Jiuru
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Indapamide to Treat Meniere's Disease
Archives of Otolaryngology - Head and Neck Surgery, 1991To the Editor .—Diuretic therapy is a mainstay in the medical treatment of Meniere's disease. 1 In our practice, as well as in many other large otologic practices, the drug of choice has been a fixed combination of hydrochlorothiazide and the potassium-sparing diuretic triamterene (Dyazide).
Hayes H. Wanamaker +2 more
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Evaluation of Indapamide in the Treatment of Hypertension
Journal of Cardiovascular Pharmacology, 1979A randomized double-blind, crossover trial was carried out in twenty hypertensive patients to evaluate the hypotensive efficacy and safety of indapamide. Indapamide in doses of 2.5 mg per day in combination with other antihypertensive agents was as effective in reducing the blood pressure in hypertensive patients as one tablet of Moduretic (50 mg ...
William J. Louis +3 more
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Fluorometric Assay for Urinary Indapamide
Journal of Pharmaceutical Sciences, 1978A sensitive fluorescence method for the determination of indapamide was developed. Reaction of indapamide with sodium hydroxide at 100 degrees yielded a fluorescent product, and addition of formaldehyde to the fluorescent product increased its fluorescence intensity by a factor of three. The assay is sensitive to levels of indapamide of 0.025 microgram/
Jo A. Treitman +2 more
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Heat capacity and enthalpy of indapamide
Thermochimica Acta, 2019Abstract The heat capacities and total enthalpy of anhydrous indapamide (IND, CAS no.: 26807-65-8) are reported from temperature 1.84 to 523.15 K measured by a Quantum Design Physical Property Measurement System® (PPMS) and differential scanning calorimetry (DSC). The low-temperature experimental heat capacities of crystalline IND from 1.84 to 302.65
Jason J. Calvin +6 more
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