Results 41 to 50 of about 9,808 (274)

Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.
ABSTRACT Cyanide is widely recognized for its potent toxicity, yet evidence shows that concentrations below 1 μM may enhance cytochrome c oxidase activity and have a regulatory function. Recent findings also demonstrate that mammalian cells, including endothelial cells, produce cyanide endogenously, where it can modulate mitochondrial bioenergetics ...
Elif Alan‐Albayrak, Ulf Simonsen
wiley   +1 more source

COMPARATIVE EFFICACY OF LONG-TERM ANTIHYPERTENSIVE MONOTHERAPY IN PATIENTS WITH ARTERIAL HYPERTENSION AT THE WORK PLACE

Рациональная фармакотерапия в кардиологии, 2016
Aim. To compare effects of 12-month monotherapy with nebivolol, enalapril and indapamide on blood pressure (BP), left ventricular hypertrophy and quality of life in the locomotive engineers and their assistants with stress-associated hypertension at the ...
О. N. Antropova, I. V. Osipova, E. I. Kuznetzova, N. V. Piricova, I. I. Curbatova   +4 more
doaj   +1 more source

Medication‐Related Osteonecrosis of the Jaws in Patients on Antiresorptive Medication With Dental Implants. A Scoping Review

Clinical Oral Implants Research, Volume 36, Issue 10, Page 1173-1201, October 2025.
ABSTRACT Objectives Patients receiving antiresorptive medication (AR) for osteoporosis or cancer are at risk of medication‐related osteonecrosis of the jaws (MRONJ), especially after surgical procedures. Dental implant (DI) placement in high‐dose AR (HDAR) patients is widely discouraged, and thorough counseling is recommended for low‐dose AR (LDAR ...
Sanne Werner Moeller Andersen, Nishma Vandvig Hindocha, Iben Poulsen, Henning Schliephake, Simon Storgård Jensen   +4 more
wiley   +1 more source

Optimal Organ Protection and Blood Pressure Control with the Single Pill Combination Lisinopril, Amlodipine and Indapamide in Arterial Hypertension

Рациональная фармакотерапия в кардиологии, 2020
Aim. To evaluate the single pill combination with lisinopril, amlodipine and indapamide ability in additional angioprotection achievement in patients with arterial hypertension and high pulse wave velocity (PWV) regardless on previous antihypertensive ...
S. V. Nedogoda, T. N. Sanina, V. V. Tsoma, A. A. Ledyaeva, E. V. Chumachek, A. S. Salasyuk, D. S. Vlasov, O. I. Bychkova   +7 more
doaj   +1 more source

Simulating a Specialist's Treatment Experience for Hypertension Using Deep Neural Networks

The Journal of Clinical Hypertension, Volume 27, Issue 10, October 2025.
ABSTRACT Hypertension management requires precise treatment decisions that balance medication efficacy with patient‐specific factors. While clinical guidelines exist, physician decision‐making often incorporates nuanced experience that remains challenging to quantify.
Jong‐Chol Ri, Kum‐Ryong Jo, Tae‐Ok Mun   +2 more
wiley   +1 more source

Indapamide Increases IRS1 Expression and Modifies Adiponectin/NLRP3/PPARγ Crosstalk in Type 2 Diabetic Rats

Antioxidants, 2022
The current study aimed to evaluate the anti-diabetic effects of canagliflozin (CANA) and indapamide (INDA) and their impacts as adiponectin modulators in experimentally induced type 2 diabetes mellitus (T2DM). T2DM was associated with a significant rise
Mahmoud M. Samaha, Manar G. Helal, Mohamed El-Sherbiny, Eman Said, Hatem A. Salem   +4 more
doaj   +1 more source

Prior events predict cerebrovascular and coronary outcomes in the PROGRESS trial [PDF]

, 2006
<p><b>Background and Purpose:</b> The relationship between baseline and recurrent vascular events may be important in the targeting of secondary prevention strategies. We examined the relationship between initial event and various types
C. Anderson, C. Tzourio, H. Arima, J. Chalmers, J. L. Reid, K. Butcher, K. R. Lees, M. Woodward, M.-G. Bousser, null null, S. MacMahon, T. Omae   +11 more
core   +2 more sources

Efficacy of Indapamide in Central Diabetes Insipidus [PDF]

Archives of Internal Medicine, 1999
Central diabetes insipidus (CDI) results from deficient vasopressin (antidiuretic hormone) secretion and causes polydipsia and polyuria. Desmopressin, a synthetic analog of vasopressin, is the drug of choice in the treatment of CDI, but in mild cases, there are alternative drugs that can be used, including chlorpropamide, carbamazepine, and thiazides ...
Murat Sert, Mustafa Koçak, Tamer Tetiker   +2 more
openaire   +3 more sources

Retrospective analysis of influences of sacubitril/valsartan in patients with diabetes with poorly controlled blood pressure in Japan

Journal of Diabetes Investigation, Volume 16, Issue 10, Page 1859-1869, October 2025.
Sacubitoril/valsartan vs thiazide in patients with diabetes. ABSTRACT Aims Achieving optimal blood pressure control remains challenging, particularly for patients with diabetes. This post‐hoc study compared the efficacy and safety of switching to sacubitril/valsartan vs adding thiazide diuretics in this population.
Shun Ito, Kazuo Kobayashi, Mari Sotozawa, Kyoji Chiba, Keiichi Chin, Hideo Shimura, Toshinao Tsuge, Hiroyuki Sakai, Takayuki Furuki, Atsushi Matsuzaki, Shinichi Nakajima, Nobukazu Takada, Hareaki Yamamoto, Hiroshi Takeda, Hiromichi Wakui, Takamasa Iwasawa, Togo Aoyama, Kouichi Tamura, Masao Toyoda, Akira Kanamori   +19 more
wiley   +1 more source

Arterial hypertension treatment effectiveness in elderly patients

Российский кардиологический журнал, 2008
Six-month indapamide therapy was highly effective in 70 % of elderly patients with Stage I-II arterial hypertension (AH). In 30 %, a combination of indapamide with lisinopril was necessary for achieving target blood pressure (BP) levels.
M. E. Statsenko, T. G. Shcherbakova, O. E. Sporova, S. V. Belenkova, Yu. V. Kalashnikova   +4 more
doaj