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Multimodal Imaging of Retinal Changes in a Patient Taking Axitinib. [PDF]

Curr Med Imaging
Comcalı S, Coskun C, Çavdarlı C, Alp MN.   +3 more
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Zur Kenntnis der Indazole

, 1946
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C3-INDAZOLE FUNCTIONALIZATION: A REVIEW

Targets in Heterocyclic Systems, 2021
Syntheses of nitrogen heteroaromatic systems are developed for numerous potential applications, particularly as biologically active compounds. Thus, scaffolds such as pyridinones,1 pyridoquinazolines,2 or indazoles (Figure 1) are frequently observed in the structure of biologically active compounds such as protein kinases inhibitors.3 Therefore, their ...
Giraud, F., Anizon, F., Moreau, P.
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Anticonvulsant action of indazole

Epilepsy Research, 2013
Here we report that indazole is characterized as a potential anticonvulsant, inhibiting pentylenetetrazole-, electroshock- and strychnine-induced convulsions in mice (ED50's: 39.9, 43.2 and 82.4 mg/kg, respectively) but not bicuculline- and picrotoxin-induced convulsions.
Nobuko, Matsumura, Kazue, Kikuchi-Utsumi, Kentaro, Sakamaki, Masahiko, Watabe, Koji, Aoyama, Toshio, Nakaki   +5 more
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Enthalpy of formation for indazoles (indazole, 1H-indazole-3-carboxylic acid, 1H-indazole-5-carboxylic acid, 1H-indazole-6-carboxylic acid and 1-methyl-1H-indazole-6-carboxylic methyl ester): experimental and theoretical studies

Journal of Thermal Analysis and Calorimetry, 2019
The molar standard enthalpy of formation in condensed and gas phases of indazole, 1H-indazole-3-carboxylic acid, 1H-indazole-5-carboxylic acid, 1H-indazole-6-carboxylic acid and 1-methyl-1H-indazole-6-carboxylic methyl ester is reported. These properties were obtained indirectly from experimental determinations of the compounds using isoperibolic ...
E. Orozco-Guareño, J. Baudelio Campos, Maximiliano Bárcena-Soto, Bernardo Zúñiga-Gutierrez   +3 more
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Synthesis of fused bis-indazoles/indazoles via a one-pot sequential strategy

Organic & Biomolecular Chemistry, 2023
An unprecedented protocol has been developed for the synthesis of fused bis-indazoles/indazoles via a one-pot sequential strategy.
Kishan Gugulothu, Ramanna Jatoth, Peramalla Edukondalu, Anusha Vanga, Raghavender Matta, K. Shiva Kumar   +5 more
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Metal-Free Trifluoromethylation of Indazoles

The Journal of Organic Chemistry, 2018
A simple and efficient tert-butyl hydroperoxide-mediated direct trifluoromethylation of indazoles using sodium trifluoromethanesulfinate has been developed under metal-free conditions. A library of trifluoromethylated products with broad functionalities has been synthesized with moderate to good yields.
Payel Ghosh, Susmita Mondal, Alakananda Hajra   +2 more
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